AXSM

Axsome Therapeutics, Inc.
NasdaqGMUSDEQUITY Healthcare DELAYED
Last price
207.77
▼ 0.26 (0.12%)
MARKET ·

Price

Open
207.43
Prev close
208.03
Day high
210.87
Day low
206.50
Volume
734.78K
Market cap
$10.88B
P/E (TTM)
52W range
112.90 – 260.19

Trailing performance

Price return · vs SPY
Returnvs SPY
1W
-2.76% -1.4%
1M
-13.98% -17.7%
3M
-11.07% -14.2%
6M
+13.09% +2.0%
YTD
+13.76% +1.5%
1Y
+77.60% +57.6%
3Y
+194.63% +120.5%
5Y

Price return only. Dividends are not reinvested, so total return on a dividend payer will be higher than shown.

Fundamentals

TTM · reported
Market cap$10.88B
Enterprise value$10.79B
Revenue (TTM)$776.57M
Gross profit$724.04M
EBITDA$-172.92M
Net income$-191.64M
EPS (TTM)$-3.74
Free cash flow$-4.58M
Total cash$319.85M
Total debt$224.69M
Book value / share$1.59
Shares outstanding52.38M
Float44.46M
Short % of float10.11%
Dividend yield
Beta (5Y)0.73

Valuation & profitability ratios

Account required
Trailing P/E
Forward P/E41.27
PEG ratio
Price / sales
Price / book130.43
EV / revenue13.89
EV / EBITDA-62.39
Gross margin93.24%
Operating margin-23.42%
Profit margin-24.68%
Return on equity-245.10%
Return on assets-16.31%
Debt / equity269.73
Current ratio1.43
Free account required

Fourteen ratios including P/E, PEG, EV/EBITDA, margins and return on equity.

Financial statements

Annual · as reported
Last 4 fiscal years
Line item2025202420232022
Total revenue$638.50M$385.69M$270.60M$50.04M
Cost of revenue$0$0$0$0
Gross profit$0$0$0$0
R&D
SG&A
Operating income
Pre-tax income
Tax provision$0$0$0$0
Net income-$183.17M-$287.22M-$239.24M-$187.13M
EBIT$0$0$0$0

Earnings

History & consensus estimates
Reported vs expected · EPS
QuarterEst.ActualSurprise
Jun 2026 -0.78-0.99 -26.9%
Dec 2025 -0.73-0.56 +23.6%
Sep 2025 -0.88-0.94 -7.3%
Jun 2025 -1.09-0.97 +10.8%
Forward consensus
PeriodEPSAnalystsRevenueGrowth
Current quarter -0.78 11 $221.78M +47.8%
Next quarter 0.07 11 $301.29M +53.7%
Current year -2.64 11 $971.05M +52.1%
Next year 5.03 11 $1.56B +60.9%

Analyst targets & ownership

Account required
Mean target$285.42
High target$380.00
Low target$246.00
Implied upside37.37%
Analyst count21
ConsensusSTRONG BUY
Strong buy / Buy3 / 17
Hold1
Sell / Strong sell0 / 0
Held by insiders15.08%
Held by institutions74.57%
Institutions holding660
Free account required

Price targets, consensus spread, insider and institutional ownership.

Insider net activity

6m · Form 4 rollup
Net shares
-19.90K
Net selling
Buy transactions
13
254.08K shares
Sell transactions
12
273.98K shares
Net transactions
+25
Buys less sells
Sell : buy shares
1.1 : 1
Mixed
Insider-held shares
7.90M
Total on file
Bought 254.08KSold 273.98K

Insider transactions

Account required
DateInsiderAction SharesValueHeld
Aug 6, 26
TABUTEAU HERRIOT
Chief Executive Officer
SELL 49.66K $10.54M Direct
Aug 6, 26
TABUTEAU HERRIOT
Chief Executive Officer
CONVERSION 49.66K $245.84K Direct
Jul 1, 26
TABUTEAU HERRIOT
Chief Executive Officer
SELL 49.67K $11.93M Direct
Jul 1, 26
TABUTEAU HERRIOT
Chief Executive Officer
CONVERSION 49.67K $11.93M Direct
Jun 11, 26
JEFFS ROGER A
Director
SELL 572 $141.66K Direct
Jun 10, 26
COLEMAN MARK H
Director
SELL 643 $160.11K Direct
Jun 10, 26
MAHONY SUSAN M
Director
SELL 600 $145.02K Direct
Jun 9, 26
TABUTEAU HERRIOT
Chief Executive Officer
SELL 49.67K $11.97M Direct
Jun 9, 26
PIZZIE NICK
Chief Financial Officer
SELL 33.00K $7.92M Direct
Jun 9, 26
TABUTEAU HERRIOT
Chief Executive Officer
CONVERSION 49.67K $245.87K Direct
Jun 9, 26
PIZZIE NICK
Chief Financial Officer
CONVERSION 33.00K $115.50K Direct
Jun 8, 26
JEFFS ROGER A
Director
1.43K Direct
Jun 8, 26
SAAD MARK E
Director
1.43K Direct
Jun 8, 26
COLEMAN MARK H
Director
1.43K Direct
What this is, and what it is not

These are SEC Form 4 filings — officers, directors and 10% owners reporting their own trades in the company's stock. Filing is due within two business days of the transaction, so this lags reality by days, and the provider adds its own lag on top.

A sale is not automatically bearish. Executives sell on scheduled 10b5-1 plans, to cover tax on vesting equity, and to diversify. Purchases with cash are generally the more informative signal, and they are far rarer.

This does not include congressional or senate trading. That comes from STOCK Act disclosures filed with the Senate eFD system and the House Clerk, which this data source does not carry.

Free account required

Officer and director trades in their own stock, straight from Form 4 filings.

Insider holders

9 reporting
NameRelationShares heldLatest
COLEMAN MARK H
Director 434.25K Sale
JACOBSON MARK L
Chief Operating Officer 0 Sale
JEFFS ROGER A
Director 58.37K Sale
MAHONY SUSAN M
Director 829 Sale
MAIZEL ARI
Officer 0 Sale
MURDOCK HUNTER R
General Counsel 0 Sale
PIZZIE NICK
Chief Financial Officer 43.35K Sale
SAAD MARK E
Director 11.73K Conversion of Exercise of derivative security
TABUTEAU HERRIOT
Chief Executive Officer 7.35M Sale

Moving averages & technicals

Computed from 2Y daily closes
SMA 10
214.46
-3.12% from price
SMA 20
217.81
-4.61% from price
SMA 50
232.40
-10.60% from price
SMA 100
220.25
-5.67% from price
SMA 200
191.43
+8.54% from price
EMA 12
214.67
-3.21% from price
EMA 26
220.35
-5.71% from price
EMA 50
223.56
-7.06% from price
RSI (14)
37.2
Neutral
MACD (12,26,9)
-5.68
Hist -0.13
ATR (14)
7.37
3.55% of price
Realised vol 30D
42.7%
Annualised
Bollinger upper
235.22
20, 2σ
Bollinger lower
200.40
20, 2σ
50 / 200 cross
Golden
232.40 vs 191.43
Trend bias
Above 200
+8.54%

Risk profile

Daily returns · 1Y window
Beta vs SPY
0.59
Less volatile than market
Correlation to SPY
0.18
Largely independent
Realised vol 30D
42.7%
Annualised
Market vol 1Y
12.9%
SPY, annualised
Max drawdown 1Y
-18.6%
Peak to trough
Max drawdown 5Y
-53.5%
Peak to trough
ATR 14
7.37
3.55% of price
Beta (reported)
0.73
5Y monthly, from filing

Unusual options activity

Account required
Flagged3
Total notional$1.16M
Call notional$489.56K
Put notional$667.00K
Tiltbalanced
Likely opening3 of 3
SideStrikeExpiryVolumeOpen int. Vol / OINotionalIV PrintScore
CALL 220.00 Dec 18, 26
117d
250 26 9.6× $442.00K 53% mid
74
PUT 220.00 Dec 18, 26
117d
250 215 1.2× $667.00K 46% mid
53
CALL 250.00 Sep 18, 26
26d
580 578 1.0× $47.56K 47% at ask
46
How this is calculated, and what it cannot see

A contract is flagged when today's volume approaches or exceeds its open interest, the position is worth at least $40,000, and at least 150 contracts changed hands. Open interest is what was outstanding at yesterday's close, so volume above it means the flow cannot all be closing — something is being opened.

The score weights four things: volume against open interest, dollar notional, volume against the rest of that chain, and where the last print sat inside the bid/ask spread.

What it cannot see. Volume here is a daily total, so ten small orders and one large one are indistinguishable — this is not block or sweep detection, which needs exchange-level time and sales. The print column compares the last trade to the current quote, which is a proxy for who was the aggressor, not a tagged flag. Quotes are delayed. A single large trade can be a hedge, a roll, or one leg of a spread, and none of those mean what a naked directional bet would mean.

Free account required

Contracts trading at or above their open interest, ranked by notional and where the print landed.

Options analytics

Account required
Put / call volume
0.33
Call-heavy session
Put / call open interest
0.53
Positioning, not flow
Max pain
200.00
-3.7% from spot
ATM implied vol
48.5%
Nearest strike to spot
Skew (10% OTM)
-5.6%
Calls bid over puts
Call volume
939
Contracts, this expiry
Put volume
306
Contracts, this expiry
Heaviest call OI
240.00
1.60K contracts
Heaviest put OI
200.00
857 contracts

Max pain is the strike at which the largest dollar value of open contracts expires worthless. It describes current positioning; it is not a forecast and it moves as open interest changes.

Free account required

Put/call ratios, max pain, implied volatility skew and where open interest is concentrated.

Options chain

Account required
ExpirySpot 207.77
Calls
StrikeLastBidAskVolOIIV
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
Puts
StrikeLastBidAskVolOIIV
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
Free account required

Every listed expiry, both sides of the book, with volume, open interest and implied volatility.

PRIVATE STRATEGY · BY QUALIFICATION

The same data. A different seat.

The research you are reading is the input layer for a discretionary options program we run for a small number of qualified investors. Minimum $1,000,000.