AXSM

Axsome Therapeutics, Inc.
NasdaqGMUSDEQUITY Healthcare DELAYED
Last price
174.59
▼ 2.49 (1.41%)
MARKET · —

Price

1D — H — L — Range — Vol —
Drag pan · Pinch zoom · Hold crosshair · pick a tool then drag to draw
Open
177.01
Prev close
177.08
Day high
176.52
Day low
169.31
Volume
1.37M
Market cap
$9.13B
P/E (TTM)
—
52W range
117.30 – 260.19

Day trading desk

Current session · delayed
Gap from prior close
-0.04%
Prior close 177.08
VWAP
173.75
+0.48% from price
Relative volume
1.28×
Normal
Session range
5.14%
169.31 – 178.00
Position in range
61%
Mid range
ATR (14D)
7.22
4.13% of price
Prior day high
179.70
PDH
Prior day low
175.73
PDL
Bid / ask spread
—
Quote not published
Session volume
887.09K
Avg 692.86K

VWAP and the session figures are computed from the delayed intraday series on this page, so they lag the live tape and will not match a broker's real-time VWAP exactly. Turn on Prior day H/L/C, Opening range and Volume profile in the chart's Studies menu to see these levels drawn on price.

Trailing performance

Price return · vs SPY
Returnvs SPY
1W
-6.34% -8.3%
1M
-15.65% -16.8%
3M
-29.01% -33.5%
6M
+3.32% -14.9%
YTD
-4.54% -18.8%
1Y
+44.92% +28.5%
3Y
+149.45% +67.2%
5Y
— —

Price return only. Dividends are not reinvested, so total return on a dividend payer will be higher than shown.

Unusual options activity

Account required
Nothing crossed the thresholds in the expiries we scanned.
That is the normal state — most contracts trade well inside their existing open interest.
Free account required

Contracts trading at or above their open interest, ranked by notional and where the print landed.

Free account

5 more panels on AXSM open with an account.

Options chains and analytics, valuation ratios, insider filings, analyst targets and ownership. No card, no trial, nothing to cancel.

Insider net activity

6m · Form 4 rollup
Net shares
-13.64K
Net selling
Buy transactions
11
209.97K shares
Sell transactions
11
223.60K shares
Net transactions
+22
Buys less sells
Sell : buy shares
1.1 : 1
Mixed
Insider-held shares
7.90M
Total on file
Bought 209.97KSold 223.60K

Insider transactions

Account required
DateInsiderAction SharesValueHeld
Sep 3, 26
JACOBSON MARK L
Chief Operating Officer
SELL 10.00K $2.09M Direct
Sep 3, 26
JACOBSON MARK L
Chief Operating Officer
CONVERSION 10.00K $129.50K Direct
Aug 6, 26
TABUTEAU HERRIOT
Chief Executive Officer
SELL 49.66K $10.54M Direct
Aug 6, 26
TABUTEAU HERRIOT
Chief Executive Officer
CONVERSION 49.66K $245.84K Direct
Jul 1, 26
TABUTEAU HERRIOT
Chief Executive Officer
SELL 49.67K $11.93M Direct
Jul 1, 26
TABUTEAU HERRIOT
Chief Executive Officer
CONVERSION 49.67K $11.93M Direct
Jun 11, 26
JEFFS ROGER A
Director
SELL 572 $141.66K Direct
Jun 10, 26
COLEMAN MARK H
Director
SELL 643 $160.11K Direct
Jun 10, 26
MAHONY SUSAN M
Director
SELL 600 $145.02K Direct
Jun 9, 26
TABUTEAU HERRIOT
Chief Executive Officer
SELL 49.67K $11.97M Direct
Jun 9, 26
TABUTEAU HERRIOT
Chief Executive Officer
CONVERSION 49.67K $245.87K Direct
Jun 9, 26
PIZZIE NICK
Chief Financial Officer
SELL 33.00K $7.92M Direct
Jun 9, 26
PIZZIE NICK
Chief Financial Officer
CONVERSION 33.00K $115.50K Direct
Jun 8, 26
JEFFS ROGER A
Director
— 1.43K — Direct
What this is, and what it is not

These are SEC Form 4 filings — officers, directors and 10% owners reporting their own trades in the company's stock. Filing is due within two business days of the transaction, so this lags reality by days, and the provider adds its own lag on top.

A sale is not automatically bearish. Executives sell on scheduled 10b5-1 plans, to cover tax on vesting equity, and to diversify. Purchases with cash are generally the more informative signal, and they are far rarer.

This does not include congressional or senate trading. That comes from STOCK Act disclosures filed with the Senate eFD system and the House Clerk, which this data source does not carry.

Free account required

Officer and director trades in their own stock, straight from Form 4 filings.

Insider holders

9 reporting
NameRelationShares heldLatest
COLEMAN MARK H
Director 434.25K Sale
JACOBSON MARK L
Chief Operating Officer 0 Sale
JEFFS ROGER A
Director 58.37K Sale
MAHONY SUSAN M
Director 829 Sale
MAIZEL ARI
Officer 0 Sale
MURDOCK HUNTER R
General Counsel 0 Sale
PIZZIE NICK
Chief Financial Officer 43.35K Sale
SAAD MARK E
Director 11.73K Conversion of Exercise of derivative security
TABUTEAU HERRIOT
Chief Executive Officer 7.35M Sale

Fundamentals

TTM · reported
Market cap$9.13B
Enterprise value$9.04B
Revenue (TTM)$776.57M
Gross profit$724.04M
EBITDA$-172.92M
Net income$-191.64M
EPS (TTM)$-3.68
Free cash flow$-4.58M
Total cash$319.85M
Total debt$224.69M
Book value / share$1.59
Shares outstanding52.38M
Float44.46M
Short % of float9.29%
Dividend yield0.00%
Beta (5Y)0.85

Valuation & profitability ratios

Account required
Trailing P/E—
Forward P/E36.95
PEG ratio—
Price / sales—
Price / book109.44
EV / revenue11.64
EV / EBITDA-52.26
Gross margin93.24%
Operating margin-23.42%
Profit margin-24.68%
Return on equity-245.10%
Return on assets-16.31%
Debt / equity269.73
Current ratio1.43
Free account required

Fourteen ratios including P/E, PEG, EV/EBITDA, margins and return on equity.

Financial statements

As reported · 4 years · 5 quarters
Blank means not reported, not zero
Line item2025202420232022YoY
Total revenue $638.50M$385.69M$270.60M$50.04M +65.5%
Operating revenue $638.50M$385.69M$270.60M$50.04M +65.5%
Cost of revenue $47.48M$33.30M$26.07M$5.20M +42.6%
Gross profit $591.02M$352.39M$244.53M$44.84M +67.7%
Research & development $183.28M$187.08M$97.94M$57.95M -2.0%
Selling, general & admin $570.60M$411.36M$323.12M$159.25M +38.7%
Total operating expense $760.25M$604.83M$427.44M$221.34M +25.7%
Operating income -$169.24M-$252.44M-$182.91M-$176.50M +33.0%
Net interest income -$6.56M-$6.57M-$6.45M-$7.33M +0.2%
Pre-tax income -$183.70M-$287.13M-$238.28M-$187.13M +36.0%
Tax provision -$530.00K$85.00K$960.00K$0 -723.5%
Net income -$183.17M-$287.22M-$239.24M-$187.13M +36.2%
Net income to common -$183.17M-$287.22M-$239.24M-$187.13M +36.2%
Basic EPS -3.68-5.99-5.27-4.60 +38.6%
Diluted EPS -3.68-5.99-5.27-4.60 +38.6%
EBIT -$177.15M-$280.56M-$231.82M-$179.80M +36.9%
EBITDA -$168.08M-$272.60M-$224.99M-$175.40M +38.3%
Basic shares 49.75M47.91M45.43M40.66M +3.8%
Diluted shares 49.75M47.91M45.43M40.66M +3.8%

Options analytics

Account required
Put / call volume
0.68
Call-heavy session
Put / call open interest
—
Positioning, not flow
Max pain
135.00
-22.6% from spot
ATM implied vol
0.0%
Nearest strike to spot
Skew (10% OTM)
0.0%
Calls bid over puts
Call volume
310
Contracts, this expiry
Put volume
211
Contracts, this expiry
Heaviest call OI
135.00
0 contracts
Heaviest put OI
155.00
0 contracts

Max pain is the strike at which the largest dollar value of open contracts expires worthless. It describes current positioning; it is not a forecast and it moves as open interest changes.

Free account required

Put/call ratios, max pain, implied volatility skew and where open interest is concentrated.

Earnings

History & consensus estimates
Reported vs expected · EPS
QuarterEst.ActualSurprise
Jun 2026 -0.78-0.99 -26.9%
Mar 2026 -0.86-1.26 -46.0%
Dec 2025 -0.73-0.56 +23.6%
Sep 2025 -0.90-0.94 -4.2%
Forward consensus
PeriodEPSAnalystsRevenueGrowth
Current quarter -0.50 12 $256.73M +50.1%
Next quarter 0.05 12 $296.97M +51.5%
Current year -2.69 12 $963.34M +50.9%
Next year 4.72 12 $1.55B +60.6%

Analyst targets & ownership

Account required
Mean target$284.63
High target$380.00
Low target$246.00
Implied upside63.03%
Analyst count22
ConsensusSTRONG BUY
Strong buy / Buy3 / 18
Hold1
Sell / Strong sell0 / 0
Held by insiders15.08%
Held by institutions74.59%
Institutions holding661
Free account required

Price targets, consensus spread, insider and institutional ownership.

Moving averages & technicals

Computed from 2Y daily closes
SMA 10
186.17
-6.22% from price
SMA 20
198.37
-12.12% from price
SMA 50
206.85
-15.72% from price
SMA 100
222.72
-21.61% from price
SMA 200
200.07
-12.86% from price
EMA 12
187.63
-6.95% from price
EMA 26
196.71
-11.24% from price
EMA 50
205.09
-14.87% from price
RSI (14)
25.9
Oversold
MACD (12,26,9)
-9.08
Hist -2.42
ATR (14)
7.22
4.14% of price
Realised vol 30D
37.0%
Annualised
Bollinger upper
226.11
20, 2σ
Bollinger lower
170.64
20, 2σ
50 / 200 cross
Golden
206.85 vs 200.07
Trend bias
Below 200
-12.86%

Options chain

Account required
Expiry
Spot 174.59
Calls
StrikeLastBidAskVolOIIV
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
Puts
StrikeLastBidAskVolOIIV
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
Free account required

Every listed expiry, both sides of the book, with volume, open interest and implied volatility.

Risk profile

Daily returns · 1Y window
Beta vs SPY
0.60
Less volatile than market
Correlation to SPY
0.18
Largely independent
Realised vol 30D
37.0%
Annualised
Market vol 1Y
13.0%
SPY, annualised
Max drawdown 1Y
-31.7%
Peak to trough
Max drawdown 5Y
-53.5%
Peak to trough
ATR 14
7.22
4.14% of price
Beta (reported)
0.85
5Y monthly, from filing

Short interest

Semi-monthly exchange report · lags by ~2 weeks
Shares short
3.14M
Prior 3.21M
Change vs prior
-2.1%
Shorts covering
% of float
9.29%
Normal
% of shares out
5.99%
Against total outstanding
Days to cover
5.5
Crowded exit
Float
44.46M
Freely tradeable shares

Exchanges publish short interest twice a month with a settlement lag, so this is roughly two weeks behind. Days to cover divides shares short by average daily volume — it estimates how long covering would take, not whether it will happen.

Rating changes

244 on file
DateFirm ActionFromTo
Sep 29, 26 Deutsche Bank MAINTAINED Buy Buy
Sep 25, 26 Morgan Stanley MAINTAINED Equal-Weight Equal-Weight
Sep 23, 26 Truist Securities MAINTAINED Buy Buy
Sep 18, 26 Piper Sandler MAINTAINED Overweight Overweight
Aug 31, 26 HC Wainwright & Co. MAINTAINED Buy Buy
Aug 12, 26 Mizuho MAINTAINED Outperform Outperform
Aug 11, 26 Morgan Stanley MAINTAINED Equal-Weight Equal-Weight
Aug 11, 26 RBC Capital MAINTAINED Outperform Outperform
Aug 11, 26 Guggenheim MAINTAINED Buy Buy
Aug 11, 26 Wells Fargo MAINTAINED Overweight Overweight
Aug 11, 26 Needham MAINTAINED Buy Buy
Jul 31, 26 Mizuho MAINTAINED Outperform Outperform

Dividends & splits

Declared · from the issuer
Forward rate—
Forward yield0.00%
5-year avg yield—
Payout ratio—
Ex-dividend date—
Next pay date—
Last split—
Split date—

PRIVATE STRATEGY · BY QUALIFICATION

The same data. A different seat.

The research you are reading is the input layer for a discretionary options program we run for a small number of qualified investors. Minimum $1,000,000.