VRTX

Vertex Pharmaceuticals Incorporated
NasdaqGSUSDEQUITY Healthcare DELAYED
Last price
505.54
▲ 2.04 (0.41%)
MARKET · —

Price

1D — H — L — Range — Vol —
Drag pan · Pinch zoom · Hold crosshair · pick a tool then drag to draw
Open
503.46
Prev close
503.50
Day high
507.41
Day low
496.33
Volume
775.06K
Market cap
$127.32B
P/E (TTM)
29.26
52W range
402.58 – 560.25

Day trading desk

Current session · delayed
Gap from prior close
-0.01%
Prior close 503.50
VWAP
501.55
+0.80% from price
Relative volume
1.01×
Normal
Session range
2.23%
496.33 – 507.41
Position in range
83%
Near session high
ATR (14D)
11.85
2.34% of price
Prior day high
506.01
PDH
Prior day low
496.15
PDL
Bid / ask spread
—
Quote not published
Session volume
1.19M
Avg 1.18M

VWAP and the session figures are computed from the delayed intraday series on this page, so they lag the live tape and will not match a broker's real-time VWAP exactly. Turn on Prior day H/L/C, Opening range and Volume profile in the chart's Studies menu to see these levels drawn on price.

Trailing performance

Price return · vs SPY
Returnvs SPY
1W
-4.64% -6.6%
1M
-8.02% -9.2%
3M
+0.78% -3.7%
6M
+16.31% -1.9%
YTD
+10.80% -3.5%
1Y
+24.55% +8.1%
3Y
+44.45% -37.8%
5Y
— —

Price return only. Dividends are not reinvested, so total return on a dividend payer will be higher than shown.

Unusual options activity

Account required
Nothing crossed the thresholds in the expiries we scanned.
That is the normal state — most contracts trade well inside their existing open interest.
Free account required

Contracts trading at or above their open interest, ranked by notional and where the print landed.

Free account

5 more panels on VRTX open with an account.

Options chains and analytics, valuation ratios, insider filings, analyst targets and ownership. No card, no trial, nothing to cancel.

Insider net activity

6m · Form 4 rollup
Net shares
+15.60K
Net buying
Buy transactions
10
39.49K shares
Sell transactions
14
23.89K shares
Net transactions
+24
Buys less sells
Sell : buy shares
0.6 : 1
Mixed
Insider-held shares
537.34K
Total on file
Bought 39.49KSold 23.89K

Insider transactions

Account required
DateInsiderAction SharesValueHeld
Aug 28, 26
AMBROSE KRISTEN
Officer
STOCK 5.00K $0 Direct
Aug 27, 26
SACHS BRUCE I
Director
STOCK 6.00K $0 Direct
Jul 21, 26
TATSIS OURANIA
Officer
STOCK 8.25K $0 Direct
Jul 21, 26
SACHDEV AMIT
Officer
STOCK 8.25K $0 Direct
Jul 2, 26
MCKECHNIE DUNCAN J.
Officer
SELL 1.54K $799.78K Direct
Jul 2, 26
TATSIS OURANIA
Officer
SELL 1.50K $787.49K Direct
Jul 1, 26
LIU JOY
Officer
SELL 828 $416.24K Direct
Jun 26, 26
BOZIC CARMEN
Officer
SELL 596 $287.57K Direct
Jun 18, 26
BOZIC CARMEN
Officer
SELL 1.02K $471.41K Direct
Jun 15, 26
BOZIC CARMEN
Officer
SELL 4.06K $1.83M Direct
Jun 5, 26
BOZIC CARMEN
Officer
SELL 1.75K $785.25K Direct
Jun 1, 26
LIU JOY
Officer
SELL 828 $364.25K Direct
May 29, 26
BOZIC CARMEN
Officer
SELL 1.97K $888.30K Direct
May 15, 26
BUNNAGE MARK E.
Officer
SELL 33 $14.96K Direct
What this is, and what it is not

These are SEC Form 4 filings — officers, directors and 10% owners reporting their own trades in the company's stock. Filing is due within two business days of the transaction, so this lags reality by days, and the provider adds its own lag on top.

A sale is not automatically bearish. Executives sell on scheduled 10b5-1 plans, to cover tax on vesting equity, and to diversify. Purchases with cash are generally the more informative signal, and they are far rarer.

This does not include congressional or senate trading. That comes from STOCK Act disclosures filed with the Senate eFD system and the House Clerk, which this data source does not carry.

Free account required

Officer and director trades in their own stock, straight from Form 4 filings.

Insider holders

10 reporting
NameRelationShares heldLatest
ALTSHULER DAVID
Officer 34.48K Stock Award(Grant)
ARBUCKLE STUART A
Chief Operating Officer 100.75K Stock Award(Grant)
ATKINSON EDWARD MORROW III
Chief Technology Officer 18.43K Sale
KEWALRAMANI RESHMA
Chief Executive Officer 98.28K Sale
LEIDEN JEFFREY M
Officer and Director 38.78K Stock Award(Grant)
LIU JOY
Officer 19.13K Sale
SACHDEV AMIT
Officer 74.03K Stock Award(Grant)
SACHS BRUCE I
Director 45.00K Purchase
TATSIS OURANIA
Officer 53.57K Stock Award(Grant)
WAGNER CHARLES F JR
Chief Operating Officer 48.79K Stock Award(Grant)

Fundamentals

TTM · reported
Market cap$127.32B
Enterprise value$121.44B
Revenue (TTM)$12.59B
Gross profit$6.92B
EBITDA$5.10B
Net income$4.41B
EPS (TTM)$17.17
Free cash flow$2.63B
Total cash$7.85B
Total debt$1.98B
Book value / share$79.92
Shares outstanding253.46M
Float252.69M
Short % of float2.10%
Dividend yield0.00%
Beta (5Y)0.28

Valuation & profitability ratios

Account required
Trailing P/E29.26
Forward P/E24.98
PEG ratio1.96
Price / sales—
Price / book6.29
EV / revenue9.65
EV / EBITDA23.81
Gross margin54.96%
Operating margin38.05%
Profit margin35.00%
Return on equity23.54%
Return on assets11.93%
Debt / equity9.77
Current ratio3.19
Free account required

Fourteen ratios including P/E, PEG, EV/EBITDA, margins and return on equity.

Financial statements

As reported · 4 years · 5 quarters
Blank means not reported, not zero
Line item2025202420232022YoY
Total revenue $12.00B$11.02B$9.87B$8.93B +8.9%
Operating revenue $11.97B$11.02B$9.87B$8.93B +8.6%
Cost of revenue $1.65B$1.53B$1.26B$1.08B +7.9%
Gross profit $10.35B$9.49B$8.61B$7.85B +9.1%
Research & development $4.04B$8.26B$3.69B$2.66B -51.1%
Selling, general & admin $1.75B$1.46B$1.14B$944.70M +19.7%
Total operating expense $5.80B$9.72B$4.83B$3.60B -40.4%
Operating income $4.55B-$233.40M$3.78B$4.25B +2,051.3%
Net interest income $477.60M$567.50M$570.60M$89.80M -15.8%
Pre-tax income $4.64B$248.50M$4.38B$4.23B +1,768.5%
Tax provision $690.00M$784.10M$760.20M$910.40M -12.0%
Net income $3.95B-$535.60M$3.62B$3.32B +838.1%
Net income to common $3.95B-$535.60M$3.62B$3.32B +838.1%
Basic EPS 15.46-2.0814.0512.97 +843.3%
Diluted EPS 15.32-2.0813.8912.82 +836.5%
EBIT $4.66B$279.10M$4.42B$4.29B +1,568.4%
EBITDA $4.87B$486.30M$4.61B$4.44B +900.7%
Basic shares 255.70M257.90M257.70M256.10M -0.9%
Diluted shares 258.00M257.90M260.50M259.10M +0.0%

Options analytics

Account required
Put / call volume
1.66
Put-heavy session
Put / call open interest
1.76
Positioning, not flow
Max pain
520.00
+3.5% from spot
ATM implied vol
51.7%
Nearest strike to spot
Skew (10% OTM)
+24.4%
Puts bid over calls
Call volume
239
Contracts, this expiry
Put volume
396
Contracts, this expiry
Heaviest call OI
520.00
96 contracts
Heaviest put OI
460.00
166 contracts

Max pain is the strike at which the largest dollar value of open contracts expires worthless. It describes current positioning; it is not a forecast and it moves as open interest changes.

Free account required

Put/call ratios, max pain, implied volatility skew and where open interest is concentrated.

Earnings

History & consensus estimates
Reported vs expected · EPS
QuarterEst.ActualSurprise
Jun 2026 4.754.73 -0.3%
Mar 2026 4.314.47 +3.8%
Dec 2025 5.155.03 -2.3%
Sep 2025 4.584.80 +4.9%
Forward consensus
PeriodEPSAnalystsRevenueGrowth
Current quarter -1.22 12 $3.41B +11.0%
Next quarter 4.56 13 $3.53B +10.5%
Current year 16.17 15 $13.25B +10.4%
Next year 20.11 15 $14.55B +9.8%

Analyst targets & ownership

Account required
Mean target$571.39
High target$672.00
Low target$350.00
Implied upside13.03%
Analyst count28
ConsensusBUY
Strong buy / Buy6 / 20
Hold5
Sell / Strong sell1 / 0
Held by insiders0.21%
Held by institutions97.93%
Institutions holding2.43K
Free account required

Price targets, consensus spread, insider and institutional ownership.

Moving averages & technicals

Computed from 2Y daily closes
SMA 10
515.94
-2.02% from price
SMA 20
515.42
-2.54% from price
SMA 50
519.19
-3.25% from price
SMA 100
492.00
+2.75% from price
SMA 200
474.12
+5.94% from price
EMA 12
513.45
-1.54% from price
EMA 26
517.63
-2.34% from price
EMA 50
513.57
-1.56% from price
RSI (14)
37.7
Neutral
MACD (12,26,9)
-4.18
Hist -2.32
ATR (14)
11.85
2.36% of price
Realised vol 30D
18.5%
Annualised
Bollinger upper
530.45
20, 2σ
Bollinger lower
500.38
20, 2σ
50 / 200 cross
Golden
519.19 vs 474.12
Trend bias
Above 200
+5.94%

Options chain

Account required
Expiry
Spot 505.54
Calls
StrikeLastBidAskVolOIIV
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
Puts
StrikeLastBidAskVolOIIV
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
Free account required

Every listed expiry, both sides of the book, with volume, open interest and implied volatility.

Risk profile

Daily returns · 1Y window
Beta vs SPY
0.50
Less volatile than market
Correlation to SPY
0.23
Largely independent
Realised vol 30D
18.5%
Annualised
Market vol 1Y
13.0%
SPY, annualised
Max drawdown 1Y
-15.2%
Peak to trough
Max drawdown 5Y
-29.1%
Peak to trough
ATR 14
11.85
2.36% of price
Beta (reported)
0.28
5Y monthly, from filing

Short interest

Semi-monthly exchange report · lags by ~2 weeks
Shares short
4.72M
Prior 4.15M
Change vs prior
+13.7%
Shorts adding
% of float
2.10%
Normal
% of shares out
1.86%
Against total outstanding
Days to cover
4.7
Liquid
Float
252.69M
Freely tradeable shares

Exchanges publish short interest twice a month with a settlement lag, so this is roughly two weeks behind. Days to cover divides shares short by average daily volume — it estimates how long covering would take, not whether it will happen.

Rating changes

553 on file
DateFirm ActionFromTo
Sep 28, 26 UBS MAINTAINED Buy Buy
Aug 5, 26 Truist Securities MAINTAINED Buy Buy
Aug 5, 26 Barclays MAINTAINED Overweight Overweight
Aug 4, 26 TD Cowen MAINTAINED Buy Buy
Aug 4, 26 Cantor Fitzgerald MAINTAINED Overweight Overweight
Aug 4, 26 Canaccord Genuity MAINTAINED Hold Hold
Jul 13, 26 UBS MAINTAINED Buy Buy
Jul 13, 26 Truist Securities MAINTAINED Buy Buy
Jul 7, 26 RBC Capital MAINTAINED Outperform Outperform
Jul 7, 26 Baird MAINTAINED Underperform Underperform
May 6, 26 Barclays MAINTAINED Overweight Overweight
May 5, 26 Canaccord Genuity MAINTAINED Hold Hold

Dividends & splits

Declared · from the issuer
Forward rate—
Forward yield0.00%
5-year avg yield—
Payout ratio0.00%
Ex-dividend date—
Next pay date—
Last split2:1
Split dateAug 24, 2000

PRIVATE STRATEGY · BY QUALIFICATION

The same data. A different seat.

The research you are reading is the input layer for a discretionary options program we run for a small number of qualified investors. Minimum $1,000,000.