TWST

Twist Bioscience Corporation
NasdaqGSUSDEQUITY Healthcare DELAYED
Last price
167.20
▼ 37.80 (18.44%)
MARKET · —

Price

1D — H — L — Range — Vol —
Drag pan · Pinch zoom · Hold crosshair · pick a tool then drag to draw
Open
206.00
Prev close
205.00
Day high
219.71
Day low
164.49
Volume
8.55M
Market cap
$11.07B
P/E (TTM)
—
52W range
23.30 – 219.71

Day trading desk

Current session · delayed
Gap from prior close
+9.19%
Prior close 188.67
VWAP
174.51
-4.19% from price
Relative volume
8.31×
Unusually busy
Session range
33.57%
164.49 – 219.71
Position in range
5%
Near session low
ATR (14D)
13.49
8.07% of price
Prior day high
198.10
PDH
Prior day low
183.39
PDL
Bid / ask spread
—
Quote not published
Session volume
15.21M
Avg 1.83M

VWAP and the session figures are computed from the delayed intraday series on this page, so they lag the live tape and will not match a broker's real-time VWAP exactly. Turn on Prior day H/L/C, Opening range and Volume profile in the chart's Studies menu to see these levels drawn on price.

Trailing performance

Price return · vs SPY
Returnvs SPY
1W
+14.14% +12.2%
1M
+59.27% +58.1%
3M
+125.20% +120.7%
6M
+300.55% +282.4%
YTD
+546.28% +532.0%
1Y
+568.19% +551.8%
3Y
+897.08% +814.8%
5Y
— —

Price return only. Dividends are not reinvested, so total return on a dividend payer will be higher than shown.

Unusual options activity

Account required
Nothing crossed the thresholds in the expiries we scanned.
That is the normal state — most contracts trade well inside their existing open interest.
Free account required

Contracts trading at or above their open interest, ranked by notional and where the print landed.

Free account

5 more panels on TWST open with an account.

Options chains and analytics, valuation ratios, insider filings, analyst targets and ownership. No card, no trial, nothing to cancel.

Insider net activity

6m · Form 4 rollup
Net shares
-521.83K
Net selling
Buy transactions
11
497.83K shares
Sell transactions
71
1.02M shares
Net transactions
+82
Buys less sells
Sell : buy shares
2.0 : 1
Mixed
Insider-held shares
476.58K
Total on file
Bought 497.83KSold 1.02M

Insider transactions

Account required
DateInsiderAction SharesValueHeld
Oct 2, 26
FINN PATRICK JOHN
President
SELL 25.71K $4.86M Direct
Oct 2, 26
CHO DENNIS
Officer
SELL 9.51K $1.80M Direct
Oct 2, 26
LEPROUST EMILY M
Chief Executive Officer
SELL 46.39K $8.77M Direct
Oct 2, 26
GREEN PAULA
Officer
SELL 10.09K $1.91M Direct
Oct 2, 26
WERNER ROBERT F.
Officer
SELL 1.48K $279.93K Direct
Oct 2, 26
LAPONIS ADAM
Chief Financial Officer
SELL 8.06K $1.52M Direct
Sep 21, 26
CHO DENNIS
Officer
SELL 348 $57.59K Direct
Sep 21, 26
LEPROUST EMILY M
Chief Executive Officer
SELL 1.69K $279.18K Direct
Sep 21, 26
GREEN PAULA
Officer
SELL 294 $48.65K Direct
Sep 17, 26
LEPROUST EMILY M
Chief Executive Officer
CONVERSION 208.71K $4.22M Direct
Sep 17, 26
LEPROUST EMILY M
Chief Executive Officer
SELL 356.55K $56.33M Direct
Sep 8, 26
CHO DENNIS
Officer
SELL 412 $50.52K Direct
Sep 8, 26
LEPROUST EMILY M
Chief Executive Officer
SELL 2.30K $282.28K Direct
Sep 8, 26
GREEN PAULA
Officer
SELL 907 $111.22K Direct
What this is, and what it is not

These are SEC Form 4 filings — officers, directors and 10% owners reporting their own trades in the company's stock. Filing is due within two business days of the transaction, so this lags reality by days, and the provider adds its own lag on top.

A sale is not automatically bearish. Executives sell on scheduled 10b5-1 plans, to cover tax on vesting equity, and to diversify. Purchases with cash are generally the more informative signal, and they are far rarer.

This does not include congressional or senate trading. That comes from STOCK Act disclosures filed with the Senate eFD system and the House Clerk, which this data source does not carry.

Free account required

Officer and director trades in their own stock, straight from Form 4 filings.

Insider holders

10 reporting
NameRelationShares heldLatest
CHAN NELSON C
Director 33.25K Stock Award(Grant)
CHESS ROBERT BRUCE
Director 63.61K Conversion of Exercise of derivative security
CHO DENNIS
Officer 63.79K Sale
CRANDELL KEITH L.
Director 103.62K Stock Award(Grant)
FINN PATRICK JOHN
President 185.09K Sale
GREEN PAULA
Officer 106.63K Sale
LAPONIS ADAM
Chief Financial Officer 100.58K Sale
LEPROUST EMILY M
Chief Executive Officer 567.31K Sale
RAGUSA ROBERT P.
Director 28.98K Stock Award(Grant)
WERNER ROBERT F.
Officer 42.92K Sale

Fundamentals

TTM · reported
Market cap$11.07B
Enterprise value$10.41B
Revenue (TTM)$431.80M
Gross profit$224.38M
EBITDA$-115.28M
Net income$-136.72M
EPS (TTM)$-2.42
Free cash flow$-64.82M
Total cash$166.84M
Total debt$108.59M
Book value / share$7.11
Shares outstanding66.30M
Float61.97M
Short % of float23.79%
Dividend yield0.00%
Beta (5Y)2.19

Valuation & profitability ratios

Account required
Trailing P/E—
Forward P/E-222.15
PEG ratio—
Price / sales—
Price / book23.48
EV / revenue24.11
EV / EBITDA-90.32
Gross margin51.96%
Operating margin-30.65%
Profit margin-31.66%
Return on equity-29.59%
Return on assets-13.09%
Debt / equity24.36
Current ratio2.67
Free account required

Fourteen ratios including P/E, PEG, EV/EBITDA, margins and return on equity.

Financial statements

As reported · 4 years · 5 quarters
Blank means not reported, not zero
Line item2025202420232022YoY
Total revenue $376.57M$312.97M$245.11M$203.56M +20.3%
Operating revenue $376.57M$312.97M$245.11M$203.56M +20.3%
Cost of revenue $185.57M$179.63M$155.38M$119.33M +3.3%
Gross profit $191.00M$133.35M$89.73M$84.23M +43.2%
Research & development $80.28M$90.85M$106.89M$120.31M -11.6%
Selling, general & admin $246.98M$218.40M$189.74M$212.95M +13.1%
Total operating expense $327.26M$309.25M$296.63M$333.26M +5.8%
Operating income -$136.26M-$175.90M-$206.90M-$249.02M +22.5%
Net interest income $11.36M$15.34M$14.37M$2.98M -25.9%
Pre-tax income -$76.95M-$208.17M-$203.47M-$228.27M +63.0%
Tax provision $719.00K$560.00K$1.15M-$10.41M +28.4%
Net income -$77.67M-$208.73M-$204.62M-$217.86M +62.8%
Net income to common -$77.67M-$208.73M-$204.62M-$217.86M +62.8%
Basic EPS -1.30-3.60-3.60-4.04 +63.9%
Diluted EPS -1.30-3.60-3.60-4.04 +63.9%
EBIT -$136.26M-$175.90M-$206.90M-$228.19M +22.5%
EBITDA -$111.41M-$144.47M-$177.59M-$211.68M +22.9%
Basic shares 59.81M58.02M56.88M53.88M +3.1%
Diluted shares 59.81M58.02M56.88M53.88M +3.1%

Options analytics

Account required
Put / call volume
0.65
Call-heavy session
Put / call open interest
1.55
Positioning, not flow
Max pain
170.00
+1.8% from spot
ATM implied vol
87.0%
Nearest strike to spot
Skew (10% OTM)
-6.9%
Calls bid over puts
Call volume
6.54K
Contracts, this expiry
Put volume
4.28K
Contracts, this expiry
Heaviest call OI
200.00
446 contracts
Heaviest put OI
170.00
1.11K contracts

Max pain is the strike at which the largest dollar value of open contracts expires worthless. It describes current positioning; it is not a forecast and it moves as open interest changes.

Free account required

Put/call ratios, max pain, implied volatility skew and where open interest is concentrated.

Earnings

History & consensus estimates
Reported vs expected · EPS
QuarterEst.ActualSurprise
Jun 2026 -0.28-0.56 -98.5%
Mar 2026 -0.53-0.60 -12.6%
Dec 2025 -0.52-0.50 +3.9%
Sep 2025 -0.50-0.45 +10.0%
Forward consensus
PeriodEPSAnalystsRevenueGrowth
Current quarter -0.15 3 $123.57M +24.8%
Next quarter -0.14 3 $125.83M +21.3%
Current year -0.96 4 $456.35M +21.2%
Next year -0.73 5 $541.25M +18.6%

Analyst targets & ownership

Account required
Mean target$133.75
High target$215.00
Low target$36.00
Implied upside-20.01%
Analyst count12
ConsensusBUY
Strong buy / Buy2 / 7
Hold3
Sell / Strong sell1 / 0
Held by insiders0.76%
Held by institutions117.07%
Institutions holding464
Free account required

Price targets, consensus spread, insider and institutional ownership.

Moving averages & technicals

Computed from 2Y daily closes
SMA 10
183.07
-8.67% from price
SMA 20
162.13
+26.44% from price
SMA 50
138.01
+48.54% from price
SMA 100
108.88
+53.56% from price
SMA 200
77.93
+163.06% from price
EMA 12
180.00
-7.11% from price
EMA 26
162.60
+2.83% from price
EMA 50
143.37
+16.62% from price
RSI (14)
76.0
Overbought
MACD (12,26,9)
17.41
Hist 2.91
ATR (14)
13.49
6.58% of price
Realised vol 30D
74.8%
Annualised
Bollinger upper
212.58
20, 2σ
Bollinger lower
111.68
20, 2σ
50 / 200 cross
Golden
138.01 vs 77.93
Trend bias
Above 200
+163.06%

Options chain

Account required
Expiry
Spot 167.20
Calls
StrikeLastBidAskVolOIIV
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
Puts
StrikeLastBidAskVolOIIV
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
Free account required

Every listed expiry, both sides of the book, with volume, open interest and implied volatility.

Risk profile

Daily returns · 1Y window
Beta vs SPY
-0.08
Less volatile than market
Correlation to SPY
-0.01
Largely independent
Realised vol 30D
74.8%
Annualised
Market vol 1Y
13.0%
SPY, annualised
Max drawdown 1Y
-25.5%
Peak to trough
Max drawdown 5Y
-91.5%
Peak to trough
ATR 14
13.49
6.58% of price
Beta (reported)
2.19
5Y monthly, from filing

Short interest

Semi-monthly exchange report · lags by ~2 weeks
Shares short
12.51M
Prior 14.11M
Change vs prior
-11.4%
Shorts covering
% of float
23.79%
Heavily shorted
% of shares out
18.86%
Against total outstanding
Days to cover
7.7
Crowded exit
Float
61.97M
Freely tradeable shares

Exchanges publish short interest twice a month with a settlement lag, so this is roughly two weeks behind. Days to cover divides shares short by average daily volume — it estimates how long covering would take, not whether it will happen.

Rating changes

99 on file
DateFirm ActionFromTo
Oct 1, 26 Guggenheim MAINTAINED Buy Buy
Sep 29, 26 Leerink Partners MAINTAINED Outperform Outperform
Sep 18, 26 BWS Financial MAINTAINED Sell Sell
Sep 17, 26 Leerink Partners MAINTAINED Outperform Outperform
Sep 9, 26 BWS Financial INITIATED — Sell
Sep 9, 26 UBS INITIATED — Neutral
Aug 5, 26 Piper Sandler MAINTAINED Overweight Overweight
Aug 4, 26 Baird MAINTAINED Outperform Outperform
Jul 14, 26 Canaccord Genuity MAINTAINED Buy Buy
Jul 6, 26 Evercore ISI Group DOWNGRADE Outperform In-Line
Jun 29, 26 Guggenheim MAINTAINED Buy Buy
Jun 24, 26 Barclays MAINTAINED Overweight Overweight

Dividends & splits

Declared · from the issuer
Forward rate—
Forward yield0.00%
5-year avg yield—
Payout ratio—
Ex-dividend date—
Next pay date—
Last split—
Split date—

PRIVATE STRATEGY · BY QUALIFICATION

The same data. A different seat.

The research you are reading is the input layer for a discretionary options program we run for a small number of qualified investors. Minimum $1,000,000.