SLN

Silence Therapeutics plc
NasdaqGMUSDEQUITY Healthcare DELAYED
Last price
13.27
▲ 0.10 (0.76%)
MARKET ·

Price

Drag pan · Pinch zoom · Hold crosshair · pick a tool then drag to draw
Open
13.01
Prev close
13.17
Day high
13.48
Day low
13.13
Volume
734.61K
Market cap
$824.78M
P/E (TTM)
52W range
4.19 – 17.58

Day trading desk

Current session · delayed
Gap from prior close
-1.21%
Prior close 13.17
VWAP
13.28
-0.04% from price
Relative volume
0.78×
Normal
Session range
13.01%
12.83 – 14.50
Position in range
26%
Near session low
ATR (14D)
1.22
9.17% of price
Prior day high
13.57
PDH
Prior day low
13.01
PDL
Bid / ask spread
Quote not published
Session volume
735.15K
Avg 948.36K

VWAP and the session figures are computed from the delayed intraday series on this page, so they lag the live tape and will not match a broker's real-time VWAP exactly. Turn on Prior day H/L/C, Opening range and Volume profile in the chart's Studies menu to see these levels drawn on price.

Trailing performance

Price return · vs SPY
Returnvs SPY
1W
-3.28% -1.9%
1M
+15.90% +12.2%
3M
+104.47% +101.4%
6M
+165.40% +154.3%
YTD
+118.26% +106.0%
1Y
+148.97% +129.0%
3Y
+104.15% +30.0%
5Y

Price return only. Dividends are not reinvested, so total return on a dividend payer will be higher than shown.

Unusual options activity

Account required
Flagged1
Total notional$101.90K
Call notional$101.90K
Put notional$0
Tiltcall-weighted
Likely opening0 of 1
SideStrikeExpiryVolumeOpen int. Vol / OINotionalIV PrintScore
CALL 30.00 Jan 15, 27
144d
2.04K 2.04K 1.0× $101.90K 121% at bid
46
How this is calculated, and what it cannot see

A contract is flagged when today's volume approaches or exceeds its open interest, the position is worth at least $40,000, and at least 150 contracts changed hands. Open interest is what was outstanding at yesterday's close, so volume above it means the flow cannot all be closing — something is being opened.

The score weights four things: volume against open interest, dollar notional, volume against the rest of that chain, and where the last print sat inside the bid/ask spread.

What it cannot see. Volume here is a daily total, so ten small orders and one large one are indistinguishable — this is not block or sweep detection, which needs exchange-level time and sales. The print column compares the last trade to the current quote, which is a proxy for who was the aggressor, not a tagged flag. Quotes are delayed. A single large trade can be a hedge, a roll, or one leg of a spread, and none of those mean what a naked directional bet would mean.

Free account required

Contracts trading at or above their open interest, ranked by notional and where the print landed.

Free account

5 more panels on SLN open with an account.

Options chains and analytics, valuation ratios, insider filings, analyst targets and ownership. No card, no trial, nothing to cancel.

Insider net activity

6m · Form 4 rollup
Net shares
0
Net selling
Buy transactions
0
0 shares
Sell transactions
0
Net transactions
0
Buys less sells
Sell : buy shares
Not enough filings
Insider-held shares
3.76M
Total on file

Fundamentals

TTM · reported
Market cap$824.78M
Enterprise value$555.02M
Revenue (TTM)$615.00K
Gross profit$528.00K
EBITDA$-63.94M
Net income$-59.95M
EPS (TTM)$-1.29
Free cash flow$-23.57M
Total cash$72.05M
Total debt$112.00K
Book value / share$0.81
Shares outstanding62.15M
Float37.84M
Short % of float5.15%
Dividend yield
Beta (5Y)1.41

Valuation & profitability ratios

Account required
Trailing P/E
Forward P/E-17.35
PEG ratio
Price / sales
Price / book16.30
EV / revenue902.47
EV / EBITDA-8.68
Gross margin85.85%
Operating margin-10475.61%
Profit margin0.00%
Return on equity-90.41%
Return on assets-29.65%
Debt / equity0.29
Current ratio7.42
Free account required

Fourteen ratios including P/E, PEG, EV/EBITDA, margins and return on equity.

Financial statements

As reported · 4 years · 6 quarters
Blank means not reported, not zero
Line item2025202420232022YoY
Total revenue $559.00K$43.26M$31.64M$21.66M -98.7%
Operating revenue $559.00K$43.26M$31.64M$21.66M -98.7%
Cost of revenue $215.00K$11.81M$12.87M$13.46M -98.2%
Gross profit $344.00K$31.45M$18.78M$8.19M -98.9%
Research & development $67.75M$67.88M$56.94M$43.55M -0.2%
Selling, general & admin $22.34M$26.88M$26.22M$25.68M -16.9%
Total operating expense $90.10M$94.77M$83.16M$69.23M -4.9%
Operating income -$89.75M-$63.32M-$64.38M-$61.04M -41.7%
Net interest income $3.48M$4.47M$1.80M$280.00K -22.2%
Pre-tax income -$88.60M-$44.46M-$53.27M-$49.65M -99.3%
Tax provision $11.00K$845.00K$956.00K$688.00K -98.7%
Net income -$88.61M-$45.31M-$54.23M-$50.33M -95.6%
Net income to common -$88.61M-$45.31M-$54.23M-$50.33M -95.6%
Basic EPS -1.89-0.99-1.47-1.56 -90.9%
Diluted EPS -1.89-0.99-1.47-1.56 -90.9%
EBIT -$89.75M-$63.32M-$64.38M-$61.04M -41.7%
EBITDA -$89.20M-$62.73M-$63.76M-$60.44M -42.2%
Basic shares 47.23M46.25M37.09M32.19M +2.1%
Diluted shares 47.23M46.25M37.09M32.19M +2.1%

Options analytics

Account required
Put / call volume
1.11
Put-heavy session
Put / call open interest
0.98
Positioning, not flow
Max pain
15.00
+13.0% from spot
ATM implied vol
143.4%
Nearest strike to spot
Skew (10% OTM)
-3.9%
Calls bid over puts
Call volume
45
Contracts, this expiry
Put volume
50
Contracts, this expiry
Heaviest call OI
15.00
4.07K contracts
Heaviest put OI
12.50
6.48K contracts

Max pain is the strike at which the largest dollar value of open contracts expires worthless. It describes current positioning; it is not a forecast and it moves as open interest changes.

Free account required

Put/call ratios, max pain, implied volatility skew and where open interest is concentrated.

Earnings

History & consensus estimates
Reported vs expected · EPS
QuarterEst.ActualSurprise
Jun 2026 -0.11-0.27 -145.5%
Mar 2026 -0.09-0.33 -266.7%
Jun 2025 -0.18-0.57 -219.3%
Sep 2025 -0.21-0.15 +27.4%
Forward consensus
PeriodEPSAnalystsRevenueGrowth
Current quarter -0.16 4 $20.67K -83.0%
Next quarter -0.17 2 $4.50K -82.3%
Current year -0.73 2 $324.74K -22.4%
Next year -0.77 2 $750.53K +131.1%

Analyst targets & ownership

Account required
Mean target$33.00
High target$75.00
Low target$10.00
Implied upside148.68%
Analyst count6
ConsensusBUY
Strong buy / Buy1 / 5
Hold0
Sell / Strong sell1 / 0
Held by insiders7.97%
Held by institutions38.33%
Institutions holding90
Free account required

Price targets, consensus spread, insider and institutional ownership.

Moving averages & technicals

Computed from 2Y daily closes
SMA 10
13.99
-5.16% from price
SMA 20
12.70
+4.50% from price
SMA 50
10.75
+23.40% from price
SMA 100
8.72
+52.09% from price
SMA 200
7.31
+81.55% from price
EMA 12
13.30
-0.22% from price
EMA 26
12.40
+7.02% from price
EMA 50
11.10
+19.54% from price
RSI (14)
56.6
Neutral
MACD (12,26,9)
0.90
Hist -0.08
ATR (14)
1.22
9.17% of price
Realised vol 30D
101.5%
Annualised
Bollinger upper
15.53
20, 2σ
Bollinger lower
9.86
20, 2σ
50 / 200 cross
Golden
10.75 vs 7.31
Trend bias
Above 200
+81.55%

Options chain

Account required
ExpirySpot 13.27
Calls
StrikeLastBidAskVolOIIV
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
Puts
StrikeLastBidAskVolOIIV
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
Free account required

Every listed expiry, both sides of the book, with volume, open interest and implied volatility.

Risk profile

Daily returns · 1Y window
Beta vs SPY
1.52
More volatile than market
Correlation to SPY
0.23
Largely independent
Realised vol 30D
101.5%
Annualised
Market vol 1Y
12.9%
SPY, annualised
Max drawdown 1Y
-41.9%
Peak to trough
Max drawdown 5Y
-91.7%
Peak to trough
ATR 14
1.22
9.17% of price
Beta (reported)
1.41
5Y monthly, from filing

Short interest

Semi-monthly exchange report · lags by ~2 weeks
Shares short
1.84M
Prior 1.73M
Change vs prior
+6.0%
Shorts adding
% of float
5.15%
Normal
% of shares out
3.89%
Against total outstanding
Days to cover
3.4
Liquid
Float
37.84M
Freely tradeable shares

Exchanges publish short interest twice a month with a settlement lag, so this is roughly two weeks behind. Days to cover divides shares short by average daily volume — it estimates how long covering would take, not whether it will happen.

Rating changes

60 on file
DateFirm ActionFromTo
Aug 11, 26 Morgan Stanley MAINTAINED Overweight Overweight
Jun 24, 26 Cantor Fitzgerald INITIATED Overweight
Jun 17, 26 HC Wainwright & Co. MAINTAINED Buy Buy
Mar 13, 26 HC Wainwright & Co. MAINTAINED Buy Buy
Sep 16, 25 HC Wainwright & Co. MAINTAINED Buy Buy
Aug 8, 25 Chardan Capital MAINTAINED Buy Buy
Jun 13, 25 HC Wainwright & Co. MAINTAINED Buy Buy
Jun 13, 25 Chardan Capital MAINTAINED Buy Buy
May 9, 25 Goldman Sachs MAINTAINED Sell Sell
May 9, 25 Morgan Stanley MAINTAINED Overweight Overweight
May 9, 25 Chardan Capital MAINTAINED Buy Buy
Mar 7, 25 HC Wainwright & Co. MAINTAINED Buy Buy

PRIVATE STRATEGY · BY QUALIFICATION

The same data. A different seat.

The research you are reading is the input layer for a discretionary options program we run for a small number of qualified investors. Minimum $1,000,000.