SEPN
Septerna, Inc.
NasdaqGMUSDEQUITY
DELAYED
Neutral
0/100
Last price
35.45
▼ 2.42 (6.39%)
MARKET · —
Price
Chart style
Interval
Intraday intervals only cover recent history. The site picks the finest interval the range allows.
Overlays
Session levels
Lower pane
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Both series are rebased to 0% at the left edge, so the lines show relative performance rather than price.
Tool
1D
—
H —
L —
Range —
Vol —
vs
Drag pan · Pinch zoom · Hold crosshair · pick a tool then drag to draw
Open
37.11
Prev close
37.87
Day high
38.69
Day low
35.60
Volume
490.44K
Market cap
—
P/E (TTM)
—
52W range
17.55 – 51.10
Day trading desk
Gap from prior close
-2.01%
Prior close 37.87
VWAP
36.04
-1.64% from price
Relative volume
—
—
Session range
10.67%
34.96 – 38.69
Position in range
13%
Near session low
ATR (14D)
1.94
5.48% of price
Prior day high
38.52
PDH
Prior day low
36.82
PDL
Bid / ask spread
—
Quote not published
Session volume
920.57K
Shares traded
VWAP and the session figures are computed from the delayed intraday series on this page, so they lag the live tape and will not match a broker's real-time VWAP exactly. Turn on Prior day H/L/C, Opening range and Volume profile in the chart's Studies menu to see these levels drawn on price.
Trailing performance
Returnvs SPY
1W
-8.84%
-10.8%
1M
-2.94%
-4.1%
3M
-2.01%
-6.5%
6M
+43.60%
+25.4%
YTD
+27.94%
+13.7%
1Y
+72.49%
+56.1%
3Y
—
-82.3%
5Y
—
—
Price return only. Dividends are not reinvested, so total return on a dividend payer will be higher than shown.
Free account
3 more panels on SEPN open with an account.
Options chains and analytics, valuation ratios, insider filings, analyst targets and ownership. No card, no trial, nothing to cancel.
Fundamentals
Market cap—
Enterprise value—
Revenue (TTM)—
Gross profit—
EBITDA—
Net income—
EPS (TTM)—
Free cash flow—
Total cash—
Total debt—
Book value / share—
Shares outstanding—
Float—
Short % of float—
Dividend yield—
Beta (5Y)—
Valuation & profitability ratios
Trailing P/E—
Forward P/E—
PEG ratio—
Price / sales—
Price / book—
EV / revenue—
EV / EBITDA—
Gross margin—
Operating margin—
Profit margin—
Return on equity—
Return on assets—
Debt / equity—
Current ratio—
Fourteen ratios including P/E, PEG, EV/EBITDA, margins and return on equity.
Financial statements
| Line item | 2025 | 2024 | 2023 | 2022 | YoY |
|---|---|---|---|---|---|
| Total revenue | $45.95M | $1.07M | $151.00K | $0 | +4,174.5% |
| Operating revenue | $45.95M | $1.07M | $151.00K | $0 | +4,174.5% |
| Research & development | $97.58M | $65.34M | $35.98M | $22.04M | +49.4% |
| Selling, general & admin | $29.16M | $16.56M | $9.72M | $5.92M | +76.1% |
| Total operating expense | $126.75M | $81.90M | $45.70M | $27.97M | +54.8% |
| Operating income | -$80.80M | -$80.82M | -$45.55M | -$27.97M | +0.0% |
| Net interest income | $19.53M | $8.62M | $2.79M | $291.00K | +126.6% |
| Pre-tax income | -$48.87M | -$72.30M | $4.87M | -$27.68M | +32.4% |
| Tax provision | $12.00K | -$498.00K | $691.00K | $0 | +102.4% |
| Net income | -$48.88M | -$71.80M | $4.18M | -$27.68M | +31.9% |
| Net income to common | -$48.88M | -$71.80M | $567.00K | -$27.68M | +31.9% |
| Basic EPS | -1.10 | -7.26 | 0.03 | -1.42 | +84.8% |
| Diluted EPS | -1.10 | -7.26 | 0.03 | -1.42 | +84.8% |
| EBIT | -$80.80M | -$80.82M | -$45.55M | -$27.97M | +0.0% |
| EBITDA | -$79.19M | -$79.42M | -$44.70M | -$27.39M | +0.3% |
| Basic shares | 44.26M | 9.89M | 19.50M | 19.50M | +347.5% |
| Diluted shares | 44.26M | 9.89M | 19.50M | 19.50M | +347.5% |
| Line item | 2025 | 2024 | 2023 | 2022 | YoY |
|---|---|---|---|---|---|
| Cash & equivalents | $120.72M | $238.20M | $88.48M | $30.61M | -49.3% |
| Cash & short-term investments | $391.09M | $350.92M | $88.48M | $30.61M | +11.4% |
| Accounts receivable | $10.36M | $171.00K | $151.00K | $0 | +5,956.1% |
| Total current assets | $410.96M | $356.82M | $112.68M | $31.89M | +15.2% |
| Property, plant & equipment | $25.93M | $28.69M | $17.19M | $3.10M | -9.6% |
| Total assets | $596.19M | $456.55M | $130.87M | $36.12M | +30.6% |
| Total current liabilities | $86.93M | $12.85M | $6.91M | $5.54M | +576.6% |
| Total debt | $23.63M | $25.48M | $12.57M | $710.00K | -7.3% |
| Total liabilities | $214.26M | $36.51M | $169.24M | $80.32M | +486.9% |
| Retained earnings | -$167.25M | -$118.37M | -$46.58M | -$50.76M | -41.3% |
| Shareholder equity | $381.93M | $420.05M | -$38.37M | -$44.20M | -9.1% |
| Working capital | $324.03M | $343.98M | $105.76M | $26.35M | -5.8% |
| Net tangible assets | $381.93M | $420.05M | -$38.37M | -$44.20M | -9.1% |
| Shares issued | 44.81M | 44.42M | 42.00M | 42.00M | +0.9% |
| Line item | 2025 | 2024 | 2023 | 2022 | YoY |
|---|---|---|---|---|---|
| Net income | -$48.88M | -$71.80M | $4.18M | -$27.68M | +31.9% |
| Depreciation & amortisation | $1.60M | $1.40M | $848.00K | $577.00K | +14.5% |
| Stock-based compensation | $8.48M | $3.15M | $1.62M | $1.52M | +168.9% |
| Change in working capital | $162.78M | $248.00K | $926.00K | $1.75M | +65,535.9% |
| Operating cash flow | $110.19M | -$67.47M | -$38.72M | -$23.30M | +263.3% |
| Capital expenditure | -$518.00K | -$2.10M | -$2.88M | -$1.29M | +75.4% |
| Investing cash flow | -$229.35M | -$160.60M | $22.12M | -$1.29M | -42.8% |
| Share buybacks | -$1.00K | -$1.00K | -$1.00K | — | 0.0% |
| Financing cash flow | $1.69M | $377.78M | $74.52M | $30.05M | -99.6% |
| Free cash flow | $109.67M | -$69.57M | -$41.60M | -$24.59M | +257.6% |
| End cash position | $121.63M | $239.10M | $89.39M | $31.47M | -49.1% |
| Line item | 2026-06-30 | 2026-03-31 | 2025-12-31 | 2025-09-30 | 2025-06-30 | YoY |
|---|---|---|---|---|---|---|
| Total revenue | $26.75M | $26.52M | $24.12M | $21.50M | $119.00K | +0.8% |
| Operating revenue | $26.75M | $26.52M | $24.12M | $21.50M | $119.00K | +0.8% |
| Research & development | $35.13M | $29.54M | $31.86M | $24.26M | $22.19M | +19.0% |
| Selling, general & admin | $8.45M | $10.29M | $8.28M | $7.12M | $6.91M | -17.9% |
| Total operating expense | $43.58M | $39.82M | $40.14M | $31.38M | $29.10M | +9.4% |
| Operating income | -$16.84M | -$13.30M | -$16.02M | -$9.89M | -$28.98M | -26.6% |
| Net interest income | $4.78M | $5.03M | $5.34M | $5.57M | $4.14M | -5.1% |
| Pre-tax income | -$12.06M | -$8.30M | -$10.73M | $8.17M | -$24.84M | -45.3% |
| Tax provision | $973.00K | $337.00K | $12.00K | $0 | $0 | +188.7% |
| Net income | -$13.03M | -$8.64M | -$10.74M | $8.17M | -$24.84M | -50.9% |
| Net income to common | -$13.03M | -$8.64M | -$10.74M | $8.17M | -$24.84M | -50.9% |
| Basic EPS | -0.29 | -0.19 | -0.24 | 0.18 | -0.56 | -52.6% |
| Diluted EPS | -0.29 | -0.19 | -0.24 | 0.18 | -0.56 | -52.6% |
| EBIT | -$16.84M | -$13.30M | -$16.02M | -$9.89M | -$28.98M | -26.6% |
| EBITDA | -$16.41M | -$12.88M | -$15.62M | -$9.48M | -$28.57M | -27.4% |
| Basic shares | 45.04M | 44.76M | 44.58M | 44.34M | 44.17M | +0.6% |
| Diluted shares | 45.04M | 44.76M | 44.58M | 45.60M | 44.17M | +0.6% |
| Line item | 2026-06-30 | 2026-03-31 | 2025-12-31 | 2025-09-30 | 2025-06-30 | YoY |
|---|---|---|---|---|---|---|
| Cash & equivalents | $84.66M | $71.61M | $120.72M | $319.99M | $189.31M | +18.2% |
| Cash & short-term investments | $372.32M | $347.40M | $391.09M | $474.35M | $326.56M | +7.2% |
| Accounts receivable | $12.16M | $10.84M | $10.36M | $8.64M | $151.00K | +12.2% |
| Total current assets | $396.15M | $368.06M | $410.96M | $491.68M | $334.14M | +7.6% |
| Property, plant & equipment | $24.26M | $25.26M | $25.93M | $26.35M | $27.25M | -4.0% |
| Total assets | $566.74M | $569.69M | $596.19M | $606.65M | $415.23M | -0.5% |
| Total current liabilities | $79.32M | $78.17M | $86.93M | $75.28M | $15.13M | +1.5% |
| Total debt | $22.55M | $23.09M | $23.63M | $24.11M | $24.57M | -2.4% |
| Total liabilities | $180.02M | $191.23M | $214.26M | $217.92M | $37.67M | -5.9% |
| Retained earnings | -$188.92M | -$175.89M | -$167.25M | -$156.51M | -$164.69M | -7.4% |
| Shareholder equity | $386.72M | $378.46M | $381.93M | $388.73M | $377.56M | +2.2% |
| Working capital | $316.84M | $289.89M | $324.03M | $416.40M | $319.01M | +9.3% |
| Net tangible assets | $386.72M | $378.46M | $381.93M | $388.73M | $377.56M | +2.2% |
| Shares issued | 45.67M | 44.92M | 44.81M | 44.64M | 44.57M | +1.7% |
| Line item | 2026-06-30 | 2026-03-31 | 2025-12-31 | 2025-09-30 | 2025-06-30 | 2025-03-31 | YoY |
|---|---|---|---|---|---|---|---|
| Net income | -$13.03M | -$8.64M | -$10.74M | $8.17M | -$24.84M | — | -50.9% |
| Depreciation & amortisation | $427.00K | $421.00K | $401.00K | $401.00K | $405.00K | — | +1.4% |
| Stock-based compensation | $5.07M | $6.01M | $2.66M | $2.53M | $1.81M | — | -15.6% |
| Change in working capital | -$14.75M | -$23.25M | -$6.99M | $170.27M | $2.78M | — | +36.5% |
| Operating cash flow | -$22.18M | -$25.63M | -$14.99M | $168.81M | -$20.29M | — | +13.5% |
| Capital expenditure | — | -$832.00K | -$65.00K | -$13.00K | -$58.00K | -$382.00K | — |
| Investing cash flow | $18.41M | -$23.82M | -$185.30M | -$38.39M | -$786.00K | — | +177.3% |
| Share buybacks | — | — | $0 | — | — | $0 | — |
| Financing cash flow | $16.82M | $333.00K | $1.02M | $263.00K | $339.00K | — | +4,952.3% |
| Free cash flow | -$22.18M | -$26.46M | -$15.05M | $168.79M | -$20.34M | — | +16.2% |
| End cash position | $85.57M | $72.51M | $121.63M | $320.89M | $190.22M | — | +18.0% |
Analyst targets & ownership
Mean target—
High target—
Low target—
Implied upside—
Analyst count—
Consensus—
Strong buy / Buy— / —
Hold—
Sell / Strong sell— / —
Held by insiders—
Held by institutions—
Institutions holding—
Price targets, consensus spread, insider and institutional ownership.
Moving averages & technicals
SMA 10
38.17
-7.11% from price
SMA 20
38.49
-7.33% from price
SMA 50
39.22
-9.05% from price
SMA 100
35.97
-1.44% from price
SMA 200
30.98
+15.13% from price
EMA 12
38.05
-6.83% from price
EMA 26
38.44
-7.78% from price
EMA 50
38.01
-6.73% from price
RSI (14)
37.9
Neutral
MACD (12,26,9)
-0.39
Hist -0.25
ATR (14)
1.94
5.45% of price
Realised vol 30D
39.2%
Annualised
Bollinger upper
40.44
20, 2σ
Bollinger lower
36.55
20, 2σ
50 / 200 cross
Golden
39.22 vs 30.98
Trend bias
Above 200
+15.13%
Options chain
Calls
| Strike | Last | Bid | Ask | Vol | OI | IV |
|---|---|---|---|---|---|---|
| 000.00 | 0.00 | 0.00 | 0.00 | 0 | 0 | 0.0% |
| 000.00 | 0.00 | 0.00 | 0.00 | 0 | 0 | 0.0% |
| 000.00 | 0.00 | 0.00 | 0.00 | 0 | 0 | 0.0% |
| 000.00 | 0.00 | 0.00 | 0.00 | 0 | 0 | 0.0% |
| 000.00 | 0.00 | 0.00 | 0.00 | 0 | 0 | 0.0% |
| 000.00 | 0.00 | 0.00 | 0.00 | 0 | 0 | 0.0% |
| 000.00 | 0.00 | 0.00 | 0.00 | 0 | 0 | 0.0% |
Puts
| Strike | Last | Bid | Ask | Vol | OI | IV |
|---|---|---|---|---|---|---|
| 000.00 | 0.00 | 0.00 | 0.00 | 0 | 0 | 0.0% |
| 000.00 | 0.00 | 0.00 | 0.00 | 0 | 0 | 0.0% |
| 000.00 | 0.00 | 0.00 | 0.00 | 0 | 0 | 0.0% |
| 000.00 | 0.00 | 0.00 | 0.00 | 0 | 0 | 0.0% |
| 000.00 | 0.00 | 0.00 | 0.00 | 0 | 0 | 0.0% |
| 000.00 | 0.00 | 0.00 | 0.00 | 0 | 0 | 0.0% |
| 000.00 | 0.00 | 0.00 | 0.00 | 0 | 0 | 0.0% |
Every listed expiry, both sides of the book, with volume, open interest and implied volatility.
Risk profile
Beta vs SPY
0.94
Less volatile than market
Correlation to SPY
0.18
Largely independent
Realised vol 30D
39.2%
Annualised
Market vol 1Y
13.0%
SPY, annualised
Max drawdown 1Y
-26.0%
Peak to trough
Max drawdown 5Y
-81.5%
Peak to trough
ATR 14
1.94
5.45% of price
Beta (reported)
—
5Y monthly, from filing
Headlines
Septerna (SEPN) Heads To Healthcare Conferences, Is The Valuation Already Too Rich?
Simply Wall St. · 23d ago
Septerna, Inc. Announces Inducement Grant Under Nasdaq Listing Rule 5635(c)(4)
GlobeNewswire · 26d ago
Septerna to Participate in Upcoming Investor Conferences
GlobeNewswire · 36d ago
Septerna Appoints Industry Veteran Rajiv Patni, M.D., as Chief Medical Officer
GlobeNewswire · 43d ago
Septerna, Inc. (SEPN) Reports Q2 Loss, Beats Revenue Estimates
Zacks · 57d ago
Septerna Q2 Loss Narrows, Revenue Rises
MT Newswires · 57d ago
Septerna Highlights Business Progress and Reports Second Quarter 2026 Financial Results
GlobeNewswire · 57d ago
Entrada Therapeutics, Inc. (TRDA) Reports Q2 Loss, Tops Revenue Estimates
Zacks · 63d ago
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