QURE

uniQure N.V.
NasdaqGSUSDEQUITY Healthcare DELAYED
Last price
48.72
▼ 0.17 (0.34%)
MARKET ·

Price

Open
49.73
Prev close
48.89
Day high
49.85
Day low
48.19
Volume
651.01K
Market cap
$3.36B
P/E (TTM)
52W range
8.73 – 71.50

Trailing performance

Price return · vs SPY
Returnvs SPY
1W
-0.51% +0.9%
1M
+22.67% +18.9%
3M
+95.36% +92.3%
6M
+106.44% +95.4%
YTD
+102.13% +89.8%
1Y
+212.47% +192.5%
3Y
+468.39% +394.2%
5Y

Price return only. Dividends are not reinvested, so total return on a dividend payer will be higher than shown.

Fundamentals

TTM · reported
Market cap$3.36B
Enterprise value$3.10B
Revenue (TTM)$18.67M
Gross profit$-114.71M
EBITDA$-182.92M
Net income$-252.21M
EPS (TTM)$-4.06
Free cash flow$-77.58M
Total cash$810.33M
Total debt$552.17M
Book value / share$4.67
Shares outstanding69.37M
Float57.52M
Short % of float15.61%
Dividend yield
Beta (5Y)0.94

Valuation & profitability ratios

Account required
Trailing P/E
Forward P/E-15.95
PEG ratio
Price / sales
Price / book10.35
EV / revenue165.87
EV / EBITDA-16.93
Gross margin0.00%
Operating margin-872.23%
Profit margin0.00%
Return on equity-157.61%
Return on assets-15.72%
Debt / equity170.40
Current ratio10.01
Free account required

Fourteen ratios including P/E, PEG, EV/EBITDA, margins and return on equity.

Financial statements

Annual · as reported
Last 4 fiscal years
Line item2025202420232022
Total revenue$13.62M$26.06M$14.60M$100.92M
Cost of revenue$0$0$0$0
Gross profit$0$0$0$0
R&D
SG&A
Operating income
Pre-tax income
Tax provision$0$0$0$0
Net income-$168.39M-$230.21M-$284.26M-$120.17M
EBIT$0$0$0$0

Earnings

History & consensus estimates
Reported vs expected · EPS
QuarterEst.ActualSurprise
Jun 2026 -0.71-1.07 -51.2%
Mar 2026 -0.75-0.73 +3.3%
Dec 2025 -0.78-0.47 +39.3%
Sep 2025 -0.75-1.19 -59.8%
Forward consensus
PeriodEPSAnalystsRevenueGrowth
Current quarter -0.82 9 $5.45M +70.5%
Next quarter -0.80 9 $6.92M +46.8%
Current year -3.44 9 $21.35M +56.7%
Next year -2.59 9 $112.85M +428.5%

Analyst targets & ownership

Account required
Mean target$70.33
High target$97.49
Low target$47.20
Implied upside44.34%
Analyst count11
ConsensusSTRONG BUY
Strong buy / Buy2 / 9
Hold1
Sell / Strong sell0 / 0
Held by insiders1.26%
Held by institutions97.77%
Institutions holding328
Free account required

Price targets, consensus spread, insider and institutional ownership.

Insider net activity

6m · Form 4 rollup
Net shares
-70.28K
Net selling
Buy transactions
23
469.55K shares
Sell transactions
30
539.83K shares
Net transactions
+53
Buys less sells
Sell : buy shares
1.1 : 1
Mixed
Insider-held shares
874.71K
Total on file
Bought 469.55KSold 539.83K

Insider transactions

Account required
DateInsiderAction SharesValueHeld
Jul 2, 26
KAPUSTA MATTHEW C
Chief Executive Officer
SELL 21.08K $952.05K Direct
Jul 2, 26
KAPUSTA MATTHEW C
Chief Executive Officer
CONVERSION 21.08K $408.78K Direct
Jun 30, 26
ABI-SAAB WALID
Officer
SELL 30.00K $1.39M Direct
Jun 30, 26
KAYE JACK
Director
SELL 21.17K $983.03K Direct
Jun 30, 26
KAYE JACK
Director
CONVERSION 21.17K $496.23K Direct
Jun 30, 26
ABI-SAAB WALID
Officer
CONVERSION 10.00K $55.90K Direct
Jun 26, 26
ABI-SAAB WALID
Officer
SELL 1.43K $67.20K Direct
Jun 25, 26
KAPUSTA MATTHEW C
Chief Executive Officer
SELL 35.41K $1.77M Direct
Jun 25, 26
KAPUSTA MATTHEW C
Chief Executive Officer
CONVERSION 32.84K $1.04M Direct
Jun 18, 26
KAPUSTA MATTHEW C
Chief Executive Officer
SELL 206.10K $9.37M Direct
Jun 18, 26
KAPUSTA MATTHEW C
Chief Executive Officer
CONVERSION 67.24K $1.36M Direct
Jun 17, 26
BALACHANDRAN MADHAVEN
Director
SELL 11.69K $526.49K Direct
Jun 17, 26
KAYE JACK
Director
SELL 5.29K $225.41K Direct
Jun 17, 26
BALACHANDRAN MADHAVEN
Director
CONVERSION 11.69K $291.81K Direct
What this is, and what it is not

These are SEC Form 4 filings — officers, directors and 10% owners reporting their own trades in the company's stock. Filing is due within two business days of the transaction, so this lags reality by days, and the provider adds its own lag on top.

A sale is not automatically bearish. Executives sell on scheduled 10b5-1 plans, to cover tax on vesting equity, and to diversify. Purchases with cash are generally the more informative signal, and they are far rarer.

This does not include congressional or senate trading. That comes from STOCK Act disclosures filed with the Senate eFD system and the House Clerk, which this data source does not carry.

Free account required

Officer and director trades in their own stock, straight from Form 4 filings.

Insider holders

10 reporting
NameRelationShares heldLatest
ABI-SAAB WALID
Officer 148.24K Sale
BALACHANDRAN MADHAVEN
Director 43.25K Sale
JACQUES RACHELLE SUZANNE
Director 33.90K Sale
KAPUSTA MATTHEW C
Chief Executive Officer 519.23K Sale
KLEMT CHRISTIAN
Chief Financial Officer 226.58K Sale
MEEK DAVID D
Director 39.75K Sale
O'KEEFE KYLIE
Officer 108.86K Sale
POST LEONARD E
Director 35.49K Sale
POTTS JEANNETTE
Officer 133.25K Sale
SPRINGHORN JEREMY P
Director 43.25K Sale

Moving averages & technicals

Computed from 2Y daily closes
SMA 10
47.32
+2.96% from price
SMA 20
44.89
+7.76% from price
SMA 50
42.72
+13.23% from price
SMA 100
32.39
+50.41% from price
SMA 200
27.40
+76.54% from price
EMA 12
46.93
+3.81% from price
EMA 26
44.76
+8.87% from price
EMA 50
41.29
+18.01% from price
RSI (14)
64.5
Neutral
MACD (12,26,9)
2.18
Hist 0.21
ATR (14)
1.99
4.12% of price
Realised vol 30D
45.2%
Annualised
Bollinger upper
51.65
20, 2σ
Bollinger lower
38.13
20, 2σ
50 / 200 cross
Golden
42.72 vs 27.40
Trend bias
Above 200
+76.54%

Risk profile

Daily returns · 1Y window
Beta vs SPY
-0.29
Less volatile than market
Correlation to SPY
-0.01
Largely independent
Realised vol 30D
45.2%
Annualised
Market vol 1Y
12.9%
SPY, annualised
Max drawdown 1Y
-87.2%
Peak to trough
Max drawdown 5Y
-90.1%
Peak to trough
ATR 14
1.99
4.12% of price
Beta (reported)
0.94
5Y monthly, from filing

Unusual options activity

Account required
Flagged3
Total notional$674.44K
Call notional$0
Put notional$674.44K
Tiltput-weighted
Likely opening3 of 3
SideStrikeExpiryVolumeOpen int. Vol / OINotionalIV PrintScore
PUT 40.00 Sep 18, 26
26d
363 63 5.8× $79.86K 118% at bid
70
PUT 39.00 Sep 18, 26
26d
341 41 8.3× $63.09K 118% at bid
68
PUT 50.00 Oct 16, 26
54d
457 415 1.1× $531.49K 120% at ask
60
How this is calculated, and what it cannot see

A contract is flagged when today's volume approaches or exceeds its open interest, the position is worth at least $40,000, and at least 150 contracts changed hands. Open interest is what was outstanding at yesterday's close, so volume above it means the flow cannot all be closing — something is being opened.

The score weights four things: volume against open interest, dollar notional, volume against the rest of that chain, and where the last print sat inside the bid/ask spread.

What it cannot see. Volume here is a daily total, so ten small orders and one large one are indistinguishable — this is not block or sweep detection, which needs exchange-level time and sales. The print column compares the last trade to the current quote, which is a proxy for who was the aggressor, not a tagged flag. Quotes are delayed. A single large trade can be a hedge, a roll, or one leg of a spread, and none of those mean what a naked directional bet would mean.

Free account required

Contracts trading at or above their open interest, ranked by notional and where the print landed.

Options analytics

Account required
Put / call volume
0.75
Call-heavy session
Put / call open interest
0.21
Positioning, not flow
Max pain
40.00
-17.3% from spot
ATM implied vol
105.8%
Nearest strike to spot
Skew (10% OTM)
-1.8%
Calls bid over puts
Call volume
994
Contracts, this expiry
Put volume
745
Contracts, this expiry
Heaviest call OI
60.00
1.54K contracts
Heaviest put OI
45.00
180 contracts

Max pain is the strike at which the largest dollar value of open contracts expires worthless. It describes current positioning; it is not a forecast and it moves as open interest changes.

Free account required

Put/call ratios, max pain, implied volatility skew and where open interest is concentrated.

Options chain

Account required
ExpirySpot 48.72
Calls
StrikeLastBidAskVolOIIV
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
Puts
StrikeLastBidAskVolOIIV
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
Free account required

Every listed expiry, both sides of the book, with volume, open interest and implied volatility.

PRIVATE STRATEGY · BY QUALIFICATION

The same data. A different seat.

The research you are reading is the input layer for a discretionary options program we run for a small number of qualified investors. Minimum $1,000,000.