GPCR

Structure Therapeutics Inc.
NasdaqGMUSDEQUITY Healthcare DELAYED
Last price
27.35
▼ 0.24 (0.89%)
MARKET · —

Price

1D — H — L — Range — Vol —
Drag pan · Pinch zoom · Hold crosshair · pick a tool then drag to draw
Open
27.70
Prev close
27.59
Day high
27.85
Day low
26.69
Volume
1.42M
Market cap
$1.96B
P/E (TTM)
—
52W range
25.59 – 94.90

Day trading desk

Current session · delayed
Gap from prior close
+0.40%
Prior close 27.59
VWAP
27.35
-0.02% from price
Relative volume
2.47×
Unusually busy
Session range
13.98%
26.32 – 30.00
Position in range
28%
Near session low
ATR (14D)
1.80
6.57% of price
Prior day high
28.20
PDH
Prior day low
26.41
PDL
Bid / ask spread
—
Quote not published
Session volume
2.34M
Avg 947.12K

VWAP and the session figures are computed from the delayed intraday series on this page, so they lag the live tape and will not match a broker's real-time VWAP exactly. Turn on Prior day H/L/C, Opening range and Volume profile in the chart's Studies menu to see these levels drawn on price.

Trailing performance

Price return · vs SPY
Returnvs SPY
1W
-15.97% -17.9%
1M
-41.97% -43.1%
3M
-49.95% -54.5%
6M
-49.76% -67.9%
YTD
-60.50% -74.8%
1Y
+0.70% -15.7%
3Y
-45.52% -127.8%
5Y
— —

Price return only. Dividends are not reinvested, so total return on a dividend payer will be higher than shown.

Unusual options activity

Account required
Nothing crossed the thresholds in the expiries we scanned.
That is the normal state — most contracts trade well inside their existing open interest.
Free account required

Contracts trading at or above their open interest, ranked by notional and where the print landed.

Free account

16 more panels on GPCR open with an account.

Options chains and analytics, valuation ratios, insider filings, analyst targets and ownership. No card, no trial, nothing to cancel.

Insider net activity

6m · Form 4 rollup
Net shares
0
Net selling
Buy transactions
0
0 shares
Sell transactions
0
—
Net transactions
0
Buys less sells
Sell : buy shares
—
Not enough filings
Insider-held shares
2.22M
Total on file

Insider transactions

Account required
DateInsiderAction SharesValueHeld
Sep 1, 26
LIN XICHEN
Officer
CONVERSION 17.82K $6.06K Direct
Aug 18, 26
LIN XICHEN
Officer
CONVERSION 11.82K $4.02K Direct
Aug 6, 26
BERRIOS JOHN JOSEPH
Officer
STOCK 140.77K $0 Direct
Aug 4, 26
LIN XICHEN
Officer
CONVERSION 11.82K $4.02K Direct
Jul 14, 26
LIN XICHEN
Officer
CONVERSION 23.63K $1.20M Direct
Jun 25, 26
LIN XICHEN
Officer
CONVERSION 23.63K $8.04K Direct
Apr 15, 26
LANG MATTHEW
Chief Operating Officer
STOCK 184.61K $0 Direct
Mar 19, 26
STEVENS RAYMOND C
Chief Executive Officer
STOCK 260.22K $0 Direct
Mar 19, 26
HALL ASHLEY
Officer
STOCK 47.71K $0 Direct
Mar 19, 26
MA YINGLI
Chief Technology Officer
STOCK 32.53K $0 Direct
Mar 19, 26
LIN XICHEN
Officer
STOCK 43.37K $0 Direct
Mar 19, 26
YOON JUN
Chief Financial Officer
STOCK 104.08K $0 Direct
Mar 19, 26
COLL CRESPO BLAS
Officer
STOCK 75.90K $0 Direct
Jul 1, 25
STEVENS RAYMOND C
Chief Executive Officer
STOCK 89.70K $0 Direct
What this is, and what it is not

These are SEC Form 4 filings — officers, directors and 10% owners reporting their own trades in the company's stock. Filing is due within two business days of the transaction, so this lags reality by days, and the provider adds its own lag on top.

A sale is not automatically bearish. Executives sell on scheduled 10b5-1 plans, to cover tax on vesting equity, and to diversify. Purchases with cash are generally the more informative signal, and they are far rarer.

This does not include congressional or senate trading. That comes from STOCK Act disclosures filed with the Senate eFD system and the House Clerk, which this data source does not carry.

Free account required

Officer and director trades in their own stock, straight from Form 4 filings.

Insider holders

8 reporting
NameRelationShares heldLatest
BERRIOS JOHN JOSEPH
Officer 140.77K Stock Award(Grant)
COLL CRESPO BLAS
Officer 280.88K Stock Award(Grant)
HALL ASHLEY
Officer 155.19K Stock Award(Grant)
LANG MATTHEW
Chief Operating Officer 184.61K Stock Award(Grant)
LIN XICHEN
Officer 228.96K Conversion of Exercise of derivative security
MA YINGLI
Chief Technology Officer 139.92K Stock Award(Grant)
STEVENS RAYMOND C
Chief Executive Officer 2.96M Stock Award(Grant)
YOON JUN
Chief Financial Officer 2.96M Stock Award(Grant)

Fundamentals

TTM · reported
Market cap$1.96B
Enterprise value$622.45M
Revenue (TTM)—
Gross profit—
EBITDA$-265.79M
Net income$-214.84M
EPS (TTM)$-3.02
Free cash flow$-119.06M
Total cash$1.34B
Total debt$6.23M
Book value / share$19.02
Shares outstanding71.31M
Float55.46M
Short % of float12.68%
Dividend yield0.00%
Beta (5Y)-1.37

Valuation & profitability ratios

Account required
Trailing P/E—
Forward P/E-13.00
PEG ratio—
Price / sales—
Price / book1.44
EV / revenue—
EV / EBITDA-2.34
Gross margin0.00%
Operating margin0.00%
Profit margin0.00%
Return on equity-20.21%
Return on assets-14.95%
Debt / equity0.46
Current ratio20.75
Free account required

Fourteen ratios including P/E, PEG, EV/EBITDA, margins and return on equity.

Financial statements

As reported · 4 years · 6 quarters
Blank means not reported, not zero
Line item2025202420232022YoY
Total revenue $0$0$0$0 —
Operating revenue $0$0$0$0 —
Research & development $225.25M$108.81M$70.10M$36.19M +107.0%
Selling, general & admin $61.55M$49.41M$32.67M$16.37M +24.6%
Total operating expense $186.81M$158.23M$102.78M$52.56M +18.1%
Operating income -$186.81M-$158.23M-$102.78M-$52.56M -18.1%
Net interest income $35.87M$36.01M$13.39M$1.26M -0.4%
Pre-tax income -$140.69M-$122.22M-$89.38M-$51.30M -15.1%
Tax provision $515.00K$310.00K$236.00K$17.00K +66.1%
Net income -$141.20M-$122.53M-$89.62M-$51.32M -15.2%
Net income to common -$141.20M-$122.53M-$89.62M-$52.84M -15.2%
Basic EPS -1.99-2.14-2.43-1.38 +6.8%
Diluted EPS -1.99-2.14-2.43-1.38 +6.8%
EBIT -$186.81M-$158.23M-$102.78M-$52.56M -18.1%
EBITDA -$185.48M-$157.24M-$102.48M-$52.28M -18.0%
Basic shares 70.84M57.29M36.73M38.24M +23.7%
Diluted shares 70.84M57.29M36.73M38.24M +23.7%

Options analytics

Account required
Put / call volume
1.20
Put-heavy session
Put / call open interest
0.00
Positioning, not flow
Max pain
25.00
-9.0% from spot
ATM implied vol
0.4%
Nearest strike to spot
Skew (10% OTM)
0.0%
Calls bid over puts
Call volume
194
Contracts, this expiry
Put volume
233
Contracts, this expiry
Heaviest call OI
105.00
8 contracts
Heaviest put OI
25.00
0 contracts

Max pain is the strike at which the largest dollar value of open contracts expires worthless. It describes current positioning; it is not a forecast and it moves as open interest changes.

Free account required

Put/call ratios, max pain, implied volatility skew and where open interest is concentrated.

Earnings

History & consensus estimates
Reported vs expected · EPS
QuarterEst.ActualSurprise
Jun 2026 -0.38-0.49 -28.3%
Mar 2026 -0.31-0.35 -12.9%
Dec 2025 -0.370.20 +154.2%
Sep 2025 -0.37-0.37 -0.6%
Forward consensus
PeriodEPSAnalystsRevenueGrowth
Current quarter -0.24 10 $50.00M 0.0%
Next quarter -0.49 10 $0 0.0%
Current year -1.62 11 $41.67M 0.0%
Next year -2.19 9 $45.45K -99.9%

Analyst targets & ownership

Account required
Mean target$105.78
High target$145.00
Low target$70.00
Implied upside286.84%
Analyst count15
ConsensusSTRONG BUY
Strong buy / Buy4 / 11
Hold1
Sell / Strong sell0 / 0
Held by insiders3.11%
Held by institutions97.70%
Institutions holding269
Free account required

Price targets, consensus spread, insider and institutional ownership.

Moving averages & technicals

Computed from 2Y daily closes
SMA 10
31.86
-14.18% from price
SMA 20
34.74
-20.93% from price
SMA 50
43.85
-37.36% from price
SMA 100
44.53
-38.60% from price
SMA 200
53.19
-48.35% from price
EMA 12
31.92
-14.33% from price
EMA 26
36.44
-24.95% from price
EMA 50
40.65
-32.73% from price
RSI (14)
16.5
Oversold
MACD (12,26,9)
-4.52
Hist -0.53
ATR (14)
1.80
6.54% of price
Realised vol 30D
63.7%
Annualised
Bollinger upper
42.86
20, 2σ
Bollinger lower
26.62
20, 2σ
50 / 200 cross
Death
43.85 vs 53.19
Trend bias
Below 200
-48.35%

Options chain

Account required
Expiry
Spot 27.35
Calls
StrikeLastBidAskVolOIIV
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
Puts
StrikeLastBidAskVolOIIV
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
000.000.000.000.00000.0%
Free account required

Every listed expiry, both sides of the book, with volume, open interest and implied volatility.

Risk profile

Daily returns · 1Y window
Beta vs SPY
0.98
Less volatile than market
Correlation to SPY
0.11
Largely independent
Realised vol 30D
63.7%
Annualised
Market vol 1Y
13.0%
SPY, annualised
Max drawdown 1Y
-70.7%
Peak to trough
Max drawdown 5Y
-81.0%
Peak to trough
ATR 14
1.80
6.54% of price
Beta (reported)
-1.37
5Y monthly, from filing

Short interest

Semi-monthly exchange report · lags by ~2 weeks
Shares short
6.61M
Prior 6.08M
Change vs prior
+8.6%
Shorts adding
% of float
12.68%
Elevated
% of shares out
9.26%
Against total outstanding
Days to cover
6.6
Crowded exit
Float
55.46M
Freely tradeable shares

Exchanges publish short interest twice a month with a settlement lag, so this is roughly two weeks behind. Days to cover divides shares short by average daily volume — it estimates how long covering would take, not whether it will happen.

Rating changes

61 on file
DateFirm ActionFromTo
Sep 9, 26 Citizens MAINTAINED Market Outperform Market Outperform
Aug 7, 26 Citigroup MAINTAINED Buy Buy
Aug 7, 26 Citizens MAINTAINED Market Outperform Market Outperform
Jun 11, 26 HC Wainwright & Co. MAINTAINED Buy Buy
Apr 27, 26 Canaccord Genuity INITIATED — Buy
Mar 16, 26 HC Wainwright & Co. MAINTAINED Buy Buy
Mar 2, 26 HC Wainwright & Co. MAINTAINED Buy Buy
Feb 27, 26 Citizens MAINTAINED Market Outperform Market Outperform
Jan 22, 26 JP Morgan MAINTAINED Overweight Overweight
Jan 20, 26 Guggenheim MAINTAINED Buy Buy
Dec 19, 25 HC Wainwright & Co. MAINTAINED Buy Buy
Dec 12, 25 Morgan Stanley MAINTAINED Overweight Overweight

Dividends & splits

Declared · from the issuer
Forward rate—
Forward yield0.00%
5-year avg yield—
Payout ratio—
Ex-dividend date—
Next pay date—
Last split—
Split date—

PRIVATE STRATEGY · BY QUALIFICATION

The same data. A different seat.

The research you are reading is the input layer for a discretionary options program we run for a small number of qualified investors. Minimum $1,000,000.