4582.T
SymBio Pharmaceuticals Limited
TokyoJPYEQUITY
Healthcare
DELAYED
Last price
64.00
▼ 1.00 (1.54%)
MARKET · —
Price
Chart style
Interval
Intraday intervals only cover recent history. The site picks the finest interval the range allows.
Overlays
Session levels
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Both series are rebased to 0% at the left edge, so the lines show relative performance rather than price.
Tool
1D
—
H —
L —
Range —
Vol —
vs
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Open
65.00
Prev close
65.00
Day high
65.00
Day low
63.00
Volume
1.17M
Market cap
$5.13B
P/E (TTM)
—
52W range
63.00 – 229.00
Day trading desk
Gap from prior close
0.00%
Prior close 65.00
VWAP
63.93
+0.11% from price
Relative volume
2.25×
Unusually busy
Session range
3.17%
63.00 – 65.00
Position in range
50%
Mid range
ATR (14D)
2.79
4.35% of price
Prior day high
66.00
PDH
Prior day low
64.00
PDL
Bid / ask spread
—
Quote not published
Session volume
1.78M
Avg 789.52K
VWAP and the session figures are computed from the delayed intraday series on this page, so they lag the live tape and will not match a broker's real-time VWAP exactly. Turn on Prior day H/L/C, Opening range and Volume profile in the chart's Studies menu to see these levels drawn on price.
Trailing performance
Returnvs SPY
1W
-12.33%
-11.0%
1M
-8.57%
-12.3%
3M
-20.99%
-24.1%
6M
-29.67%
-40.7%
YTD
-28.89%
-41.2%
1Y
-58.97%
-79.0%
3Y
-85.05%
-159.2%
5Y
—
—
Price return only. Dividends are not reinvested, so total return on a dividend payer will be higher than shown.
Unusual options activity
Nothing crossed the thresholds in the expiries we scanned.
That is the normal state — most contracts trade well inside their existing open interest.
That is the normal state — most contracts trade well inside their existing open interest.
Contracts trading at or above their open interest, ranked by notional and where the print landed.
Free account
5 more panels on 4582.T open with an account.
Options chains and analytics, valuation ratios, insider filings, analyst targets and ownership. No card, no trial, nothing to cancel.
Insider net activity
Net shares
0
Net selling
Buy transactions
0
0 shares
Sell transactions
0
—
Net transactions
0
Buys less sells
Sell : buy shares
—
Not enough filings
Insider-held shares
7.39M
Total on file
Fundamentals
Market cap$5.13B
Enterprise value$4.75B
Revenue (TTM)$1.13B
Gross profit$791.00M
EBITDA—
Net income$-6.03B
EPS (TTM)$-96.66
Free cash flow$-2.49B
Total cash$977.00M
Total debt$832.00M
Book value / share$-7.64
Shares outstanding80.16M
Float69.59M
Short % of float—
Dividend yield—
Beta (5Y)0.50
Valuation & profitability ratios
Trailing P/E—
Forward P/E1.64
PEG ratio—
Price / sales—
Price / book—
EV / revenue4.21
EV / EBITDA—
Gross margin70.00%
Operating margin-549.76%
Profit margin0.00%
Return on equity-677.08%
Return on assets-122.46%
Debt / equity—
Current ratio0.75
Fourteen ratios including P/E, PEG, EV/EBITDA, margins and return on equity.
Financial statements
| Line item | 2025 | 2024 | 2023 | 2022 | YoY |
|---|---|---|---|---|---|
| Total revenue | $1.31B | $2.45B | $5.59B | $10.01B | -46.7% |
| Operating revenue | $1.31B | $2.45B | $5.59B | $10.01B | -46.7% |
| Cost of revenue | $360.31M | $579.72M | $1.18B | $2.41B | -37.8% |
| Gross profit | $947.34M | $1.87B | $4.41B | $7.60B | -49.4% |
| Total operating expense | $5.39B | $5.75B | $5.22B | $5.64B | -6.3% |
| Operating income | -$4.44B | -$3.88B | -$811.67M | $1.96B | -14.5% |
| Net interest income | -$155.33M | $12.17M | $494.00K | -$45.77M | -1,376.2% |
| Pre-tax income | -$4.75B | -$3.81B | -$1.20B | $2.11B | -24.7% |
| Tax provision | $27.57M | $26.52M | $767.43M | $927.04M | +4.0% |
| Net income | -$4.78B | -$3.83B | -$1.96B | $1.18B | -24.6% |
| Net income to common | -$4.78B | -$3.83B | -$1.96B | $1.18B | -24.6% |
| Basic EPS | -95.12 | -85.00 | -49.19 | 30.20 | -11.9% |
| Diluted EPS | -95.12 | -85.00 | -49.19 | 29.77 | -11.9% |
| EBIT | -$4.71B | -$3.81B | -$811.67M | $1.96B | -23.7% |
| EBITDA | -$4.71B | -$3.81B | -$715.66M | $2.06B | -23.7% |
| Basic shares | 50.21M | 45.10M | 39.90M | 39.05M | +11.3% |
| Diluted shares | 50.21M | 45.10M | 39.90M | 39.61M | +11.3% |
| Line item | 2025 | 2024 | 2023 | 2022 | 2021 | YoY |
|---|---|---|---|---|---|---|
| Cash & equivalents | $2.88B | $3.96B | $6.52B | $6.28B | — | -27.3% |
| Cash & short-term investments | $2.88B | $3.96B | $6.52B | $6.28B | — | -27.3% |
| Accounts receivable | $259.68M | $423.15M | $913.09M | $2.08B | — | -38.6% |
| Inventory | $288.95M | $238.92M | $232.03M | $469.38M | — | +20.9% |
| Total current assets | $3.82B | $4.92B | $8.08B | $9.31B | — | -22.3% |
| Property, plant & equipment | $37.35M | $44.10M | $87.72M | $153.71M | — | -15.3% |
| Goodwill & intangibles | — | — | $0 | $222.20M | $259.10M | — |
| Total assets | $3.87B | $4.97B | $8.17B | $10.43B | — | -22.2% |
| Total current liabilities | $1.29B | $766.17M | $956.63M | $1.92B | — | +68.4% |
| Current debt | $682.50M | $0 | — | — | — | — |
| Long-term debt | $1.30B | $0 | — | — | — | — |
| Total debt | $1.98B | $0 | — | — | — | — |
| Total liabilities | $2.60B | $770.77M | $960.33M | $1.93B | — | +236.7% |
| Retained earnings | -$37.46B | -$32.69B | -$28.85B | -$26.89B | — | -14.6% |
| Shareholder equity | $1.27B | $4.20B | $7.21B | $8.51B | — | -69.7% |
| Working capital | $2.53B | $4.16B | $7.13B | $7.39B | — | -39.1% |
| Net tangible assets | $1.27B | $4.20B | $7.21B | $8.28B | — | -69.7% |
| Shares issued | 59.57M | 45.93M | 42.28M | 39.60M | — | +29.7% |
| Line item | 2025 | 2024 | 2023 | 2022 | 2021 | YoY |
|---|---|---|---|---|---|---|
| Net income | -$4.75B | -$3.81B | -$1.20B | $2.11B | — | -24.7% |
| Depreciation & amortisation | — | $0 | $96.00M | $98.09M | $93.96M | — |
| Stock-based compensation | $94.71M | $93.41M | $82.50M | $104.73M | — | +1.4% |
| Change in working capital | -$187.39M | $263.07M | $841.04M | -$59.78M | — | -171.2% |
| Operating cash flow | -$4.58B | -$3.42B | -$194.69M | $1.61B | — | -33.9% |
| Capital expenditure | -$82.47M | -$46.88M | -$232.80M | -$47.56M | — | -75.9% |
| Investing cash flow | -$75.92M | -$3.96M | -$376.70M | -$47.13M | — | -1,819.5% |
| Share buybacks | -$10.13M | -$20.44M | -$12.53M | -$48.00M | — | +50.5% |
| Financing cash flow | $3.62B | $708.47M | $680.16M | $627.99M | — | +411.2% |
| Free cash flow | -$4.66B | -$3.46B | -$427.48M | $1.57B | — | -34.5% |
| End cash position | $2.88B | $3.96B | $6.52B | $6.28B | — | -27.3% |
| Line item | 2026-03-31 | 2025-12-31 | 2025-09-30 | 2025-06-30 | 2025-03-31 | 2024-12-31 | YoY |
|---|---|---|---|---|---|---|---|
| Total revenue | — | $336.84M | $324.17M | $382.62M | $264.02M | $554.54M | — |
| Operating revenue | — | $336.84M | $324.17M | $382.62M | $264.02M | $554.54M | — |
| Cost of revenue | — | $84.95M | $122.29M | $91.46M | $61.61M | $125.69M | — |
| Gross profit | — | $251.89M | $201.88M | $291.16M | $202.41M | $428.85M | — |
| Total operating expense | — | $1.35B | $1.39B | $1.28B | $1.37B | $1.51B | — |
| Operating income | — | -$1.10B | -$1.19B | -$984.88M | -$1.17B | -$1.09B | — |
| Net interest income | — | -$14.89M | -$29.46M | -$54.87M | -$56.11M | $7.99M | — |
| Pre-tax income | — | -$1.19B | -$1.20B | -$1.05B | -$1.31B | -$981.98M | — |
| Tax provision | — | $19.46M | -$3.66M | $14.00K | $11.76M | $6.47M | — |
| Net income | — | -$1.21B | -$1.20B | -$1.05B | -$1.32B | -$988.46M | — |
| Net income to common | — | -$1.21B | -$1.20B | -$1.05B | -$1.32B | -$988.46M | — |
| Basic EPS | -35.89 | — | — | — | -27.95 | — | — |
| Diluted EPS | -35.89 | — | — | — | -27.95 | — | — |
| EBIT | — | -$1.18B | -$1.19B | -$1.04B | -$1.30B | -$1.05B | — |
| EBITDA | — | -$1.18B | -$1.19B | -$1.04B | -$1.30B | -$1.05B | — |
| Basic shares | 66.91M | — | — | — | 47.28M | — | — |
| Diluted shares | 66.91M | — | — | — | 47.28M | — | — |
| Line item | 2025-12-31 | 2025-09-30 | 2025-06-30 | 2025-03-31 | 2024-12-31 | YoY |
|---|---|---|---|---|---|---|
| Cash & equivalents | $2.88B | $3.46B | $3.05B | $3.61B | $3.96B | -16.8% |
| Cash & short-term investments | $2.88B | $3.46B | $3.05B | $3.61B | $3.96B | -16.8% |
| Accounts receivable | $259.68M | $195.63M | $205.02M | $211.66M | $423.15M | +32.7% |
| Inventory | $288.95M | $330.83M | $274.90M | $256.58M | $238.92M | -12.7% |
| Total current assets | $3.82B | $4.54B | $4.10B | $4.63B | $4.92B | -15.7% |
| Property, plant & equipment | $37.35M | $37.35M | $37.35M | $37.35M | $44.10M | 0.0% |
| Total assets | $3.87B | $4.58B | $4.14B | $4.67B | $4.97B | -15.6% |
| Total current liabilities | $1.29B | $582.77M | $470.23M | $564.56M | $766.17M | +121.4% |
| Current debt | $682.50M | — | — | — | $0 | — |
| Long-term debt | $1.30B | $2.34B | $1.30B | $700.00M | $0 | -44.4% |
| Total debt | $1.98B | $2.34B | $1.30B | $700.00M | $0 | -15.3% |
| Total liabilities | $2.60B | $2.93B | $1.78B | $1.27B | $770.77M | -11.4% |
| Retained earnings | -$37.46B | -$36.25B | -$35.05B | -$34.01B | -$32.69B | -3.3% |
| Shareholder equity | $1.27B | $1.65B | $2.36B | $3.40B | $4.20B | -23.0% |
| Working capital | $2.53B | $3.95B | $3.63B | $4.06B | $4.16B | -35.9% |
| Net tangible assets | $1.27B | $1.65B | $2.36B | $3.40B | $4.20B | -23.0% |
| Shares issued | 59.57M | 48.76M | 47.83M | 47.92M | 45.93M | +22.2% |
No filings published for this symbol yet.
Newly listed companies often have nothing on file until their first annual report.
Newly listed companies often have nothing on file until their first annual report.
Options analytics
Put / call volume
—
—
Put / call open interest
—
Positioning, not flow
Max pain
—
—
ATM implied vol
—
Nearest strike to spot
Skew (10% OTM)
—
—
Call volume
0
Contracts, this expiry
Put volume
0
Contracts, this expiry
Heaviest call OI
—
—
Heaviest put OI
—
—
Max pain is the strike at which the largest dollar value of open contracts expires worthless. It describes current positioning; it is not a forecast and it moves as open interest changes.
Put/call ratios, max pain, implied volatility skew and where open interest is concentrated.
Earnings
Reported vs expected · EPS
| Quarter | Est. | Actual | Surprise |
|---|---|---|---|
| Mar 2026 | — | -35.89 | — |
| Sep 2025 | — | -24.11 | — |
Forward consensus
| Period | EPS | Analysts | Revenue | Growth |
|---|---|---|---|---|
| Current quarter | — | — | $0 | — |
| Next quarter | — | — | $0 | — |
| Current year | — | — | $0 | — |
| Next year | — | — | $0 | — |
Analyst targets & ownership
Mean target—
High target—
Low target—
Implied upside—
Analyst count—
ConsensusNONE
Strong buy / Buy— / —
Hold—
Sell / Strong sell— / —
Held by insiders9.81%
Held by institutions4.71%
Institutions holding3
Price targets, consensus spread, insider and institutional ownership.
Moving averages & technicals
SMA 10
68.80
-6.98% from price
SMA 20
68.75
-6.91% from price
SMA 50
69.64
-8.10% from price
SMA 100
79.73
-19.73% from price
SMA 200
93.01
-31.19% from price
EMA 12
67.95
-5.81% from price
EMA 26
69.09
-7.37% from price
EMA 50
71.76
-10.81% from price
RSI (14)
36.0
Neutral
MACD (12,26,9)
-1.14
Hist -0.52
ATR (14)
2.79
4.35% of price
Realised vol 30D
39.5%
Annualised
Bollinger upper
73.31
20, 2σ
Bollinger lower
64.19
20, 2σ
50 / 200 cross
Death
69.64 vs 93.01
Trend bias
Below 200
-31.19%
Options chain
Calls
| Strike | Last | Bid | Ask | Vol | OI | IV |
|---|---|---|---|---|---|---|
| 000.00 | 0.00 | 0.00 | 0.00 | 0 | 0 | 0.0% |
| 000.00 | 0.00 | 0.00 | 0.00 | 0 | 0 | 0.0% |
| 000.00 | 0.00 | 0.00 | 0.00 | 0 | 0 | 0.0% |
| 000.00 | 0.00 | 0.00 | 0.00 | 0 | 0 | 0.0% |
| 000.00 | 0.00 | 0.00 | 0.00 | 0 | 0 | 0.0% |
| 000.00 | 0.00 | 0.00 | 0.00 | 0 | 0 | 0.0% |
| 000.00 | 0.00 | 0.00 | 0.00 | 0 | 0 | 0.0% |
Puts
| Strike | Last | Bid | Ask | Vol | OI | IV |
|---|---|---|---|---|---|---|
| 000.00 | 0.00 | 0.00 | 0.00 | 0 | 0 | 0.0% |
| 000.00 | 0.00 | 0.00 | 0.00 | 0 | 0 | 0.0% |
| 000.00 | 0.00 | 0.00 | 0.00 | 0 | 0 | 0.0% |
| 000.00 | 0.00 | 0.00 | 0.00 | 0 | 0 | 0.0% |
| 000.00 | 0.00 | 0.00 | 0.00 | 0 | 0 | 0.0% |
| 000.00 | 0.00 | 0.00 | 0.00 | 0 | 0 | 0.0% |
| 000.00 | 0.00 | 0.00 | 0.00 | 0 | 0 | 0.0% |
Every listed expiry, both sides of the book, with volume, open interest and implied volatility.
Risk profile
Beta vs SPY
-0.17
Less volatile than market
Correlation to SPY
-0.03
Largely independent
Realised vol 30D
39.5%
Annualised
Market vol 1Y
12.9%
SPY, annualised
Max drawdown 1Y
-68.2%
Peak to trough
Max drawdown 5Y
-96.4%
Peak to trough
ATR 14
2.79
4.35% of price
Beta (reported)
0.50
5Y monthly, from filing
Dividends & splits
Forward rate—
Forward yield—
5-year avg yield—
Payout ratio0.00%
Ex-dividend date—
Next pay date—
Last split1:4
Split dateJun 26, 2019
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